Summary

Market Overview
The United States Humanized Mice Model Market was valued at USD 36.31 million in 2024 and is projected to grow at a CAGR of 6.12% through 2030. Humanized mice models—laboratory mice engineered to express human genes, cells, tissues, or immune systems—have become indispensable in biomedical research. These models enable scientists to replicate human physiological processes within a living organism, bridging critical gaps between in vitro experiments and clinical trials. Their relevance spans across multiple domains, including oncology, immunology, infectious disease research, and drug development. As part of the broader shift toward human-based testing methods, initiatives by institutions like the NIH and FDA are advancing alternatives such as organ-on-chip technologies while reinforcing the importance of accurate in vivo models like humanized mice. These developments are enhancing research precision and expanding capabilities in disease modeling and therapeutic evaluation.
Key Market Drivers
Increasing Need for Personalized Medicine
The rising focus on personalized medicine is significantly driving the demand for humanized mice models in the United States. These models offer a close approximation of human physiological and genetic variability, which is critical for developing customized therapies. Their human-like immune systems make them especially suitable for evaluating targeted treatments in oncology, immunology, and chronic disease management. With a growing aging population—over 94% of individuals aged 60 and above having at least one chronic illness and nearly 78% managing multiple conditions—personalized approaches to treatment are becoming essential. Humanized mice enable researchers to test patient-specific responses to therapies, accelerating the development of precision medicine. As the U.S. continues to lead in biomedical innovation, the demand for reliable, predictive in vivo models is expected to grow in parallel with advancements in tailored healthcare solutions.
Key Market Challenges
High Costs Associated with Development of Humanized Mice Models
The considerable costs linked to the development and maintenance of humanized mice models present a significant hurdle in the U.S. market. Creating these models involves complex genetic engineering, skilled personnel, and specialized facilities for housing and care. These requirements drive up costs and can limit access for smaller research institutions or startups. Moreover, funding constraints and budget limitations often make it challenging for researchers to consistently utilize these models, despite their scientific value. As a result, some institutions may turn to alternative models that are more affordable but potentially less representative of human biology. The high cost factor could slow down broader adoption, making it essential for stakeholders to seek funding support or cost-reduction innovations to sustain growth and accessibility in the market.
Key Market Trends
Increased Use in Oncology Research
The utilization of humanized mice models in oncology research is rising significantly across the United States. These models provide an advanced platform for studying the behavior of human tumor cells and evaluating therapeutic responses in a physiologically relevant context. Their use is becoming increasingly prevalent as cancer rates grow and demand intensifies for more accurate preclinical models. Advancements in genetic engineering have enhanced model precision, making them more effective in mimicking human cancer biology. With expanding government and private funding for oncology research, as well as the development of models tailored to specific cancer types, humanized mice are playing a central role in enabling deeper insights into cancer pathogenesis and treatment efficacy. This trend is expected to further accelerate market growth as the need for translational research tools continues to expand.
Key Market Players
• Charles River Laboratories International, Inc.
• The Jackson Laboratory
• Taconic Biosciences Inc.
• Hera BioLabs
• Ingenious Targeting Laboratory Inc.
• Champions Oncology, Inc.
• Yecuris Corporation
• Crown Bioscience Inc.
• Taconic Biosciences Inc.
• HuMurine Technologies
Report Scope:
In this report, the United States Humanized Mice Model Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:
• United States Humanized Mice Model Market, By Type:
o Genetic Humanized Mice Model
o Cell-based Humanized Mice Model
• United States Humanized Mice Model Market, By Application:
o Oncology Studies
o Immunology and Inflammation Studies
o Others
• United States Humanized Mice Model Market, By End User:
o Pharmaceutical & Biotechnology Companies
o Academic & Research Institutes
o Contract Research Organizations
• United States Humanized Mice Model Market, By Region:
o Northeast Region
o Midwest Region
o West Region
o South Region
Competitive Landscape
Company Profiles: Detailed analysis of the major companies present in the United States Humanized Mice Model Market.
Available Customizations
United States Humanized Mice Model Market report with the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report:
Company Information
• Detailed analysis and profiling of additional market players (up to five).

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Table of Contents

1. Product Overview
1.1. Market Definition
1.2. Scope of the Market
1.2.1. Markets Covered
1.2.2. Years Considered for Study
1.2.3. Key Market Segmentations
2. Research Methodology
2.1. Objective of the Study
2.2. Baseline Methodology
2.3. Key Industry Partners
2.4. Major Association and Secondary Sources
2.5. Forecasting Methodology
2.6. Data Triangulation & Validation
2.7. Assumptions and Limitations
3. Executive Summary
3.1. Overview of the Market
3.2. Overview of Key Market Segmentations
3.3. Overview of Key Market Players
3.4. Overview of Key Regions/Countries
3.5. Overview of Market Drivers, Challenges, Trends
4. Voice of Customer
5. United States Humanized Mice Model Market Outlook
5.1. Market Size & Forecast
5.1.1. By Value
5.2. Market Share & Forecast
5.2.1. By Type (Genetic Humanized Mice Model, Cell-based Humanized Mice Model)
5.2.2. By Application (Oncology Studies, Immunology and Inflammation Studies, Others)
5.2.3. By End User (Pharmaceutical & Biotechnology Companies, Academic & Research Institutes, Contract Research Organizations)
5.2.4. By Region
5.2.5. By Company (2024)
5.3. Market Map
6. North-East Humanized Mice Model Market Outlook
6.1. Market Size & Forecast
6.1.1. By Value
6.2. Market Share & Forecast
6.2.1. By Type
6.2.2. By Application
6.2.3. By End User
7. Mid-West Humanized Mice Model Market Outlook
7.1. Market Size & Forecast
7.1.1. By Value
7.2. Market Share & Forecast
7.2.1. By Type
7.2.2. By Application
7.2.3. By End User
8. West Humanized Mice Model Market Outlook
8.1. Market Size & Forecast
8.1.1. By Value
8.2. Market Share & Forecast
8.2.1. By Type
8.2.2. By Application
8.2.3. By End User
9. South Humanized Mice Model Market Outlook
9.1. Market Size & Forecast
9.1.1. By Value
9.2. Market Share & Forecast
9.2.1. By Type
9.2.2. By Application
9.2.3. By End User
10. Market Dynamics
10.1. Drivers
10.2. Challenges
11. Market Trends & Developments
11.1. Recent Development
11.2. Mergers & Acquisitions
11.3. Product Launches
12. Policy & Regulatory Landscape
13. United States Economic Profile
14. United States Humanized Mice Model Market: SWOT Analysis
15. Porter’s Five Forces Analysis
15.1. Competition in the Industry
15.2. Potential of New Entrants
15.3. Power of Suppliers
15.4. Power of Customers
15.5. Threat of Substitute Products
16. Competitive Landscape
16.1. Charles River Laboratories International, Inc.
16.1.1. Business Overview
16.1.2. Product Offerings
16.1.3. Recent Developments
16.1.4. Financials (As Reported)
16.1.5. Key Personnel
16.2. The Jackson Laboratory
16.3. Taconic Biosciences Inc.
16.4. Hera BioLabs
16.5. Ingenious Targeting Laboratory Inc.
16.6. Champions Oncology, Inc.
16.7. Yecuris Corporation
16.8.Crown BioSciences Inc.
16.9. Taconic Biosciences Inc.
16.10. HuMurine Technologies
17. Strategic Recommendations
18. About Us & Disclaimer