Summary

The global market for Metformin Hydrochloride was estimated to be worth US$ 391 million in 2024 and is forecast to a readjusted size of US$ 584 million by 2031 with a CAGR of 6.3% during the forecast period 2025-2031.
This report provides a comprehensive assessment of recent tariff adjustments and international strategic countermeasures on Metformin Hydrochloride cross-border industrial footprints, capital allocation patterns, regional economic interdependencies, and supply chain reconfigurations.
Metformin hydrochloride is the raw material of finished product metformin hydrochloride drugs. That is the API metformin hydrochloride. Metformin Hydrochloride finished product is an oral antihyperglycemic drug used in the management of type 2-diabetes. Metformin hydrochloride (N, N-dimethylimidodicarbonimidic diamide hydrochloride) is not chemically or pharmacologically related to any other classes of oral antihyperglycemic agents. Metformin hydrochloride is a white to off-white crystalline compound with a molecular formula of C4H11N5·HCL and a molecular weight of 165.63. Metformin hydrochloride is freely soluble in water and is practically insoluble in acetone, ether and chloroform. In this report, our statistics is given by metformin hydrochloride API.In 2024, global Metformin Hydrochloride reached approximately 66400 MT, with an average global market price of around US$ 5894 per MT.

Metformin Hydrochloride is a widely used oral antihyperglycemic drug, primarily prescribed for the treatment of type 2 diabetes. It belongs to the biguanide class and works by reducing hepatic glucose production, decreasing intestinal absorption of glucose, and improving insulin sensitivity in peripheral tissues. Its well-established efficacy, safety profile, and low cost have made it the first-line therapy for millions of patients worldwide. The global market is highly standardized, with a production capacity of about 120,000 tons, a relatively thin gross profit margin of 6%–20%, and single-line production capacities commonly in the range of 3,000–5,000 tons, reflecting a mature, large-scale pharmaceutical intermediate market.
The industry chain begins upstream with raw materials such as dimethylamine hydrochloride and dicyandiamide, which undergo chemical synthesis to produce metformin base. This intermediate is further crystallized and refined with hydrochloric acid to yield metformin hydrochloride in pharmaceutical-grade quality. Midstream, manufacturers formulate the active pharmaceutical ingredient (API) into bulk drug products or supply it to formulation companies. Downstream, the demand is dominated by generic drug manufacturers producing tablets, extended-release formulations, and fixed-dose combinations with other antidiabetic drugs. The industry structure is characterized by significant competition among bulk producers, especially in China and India, which supply the majority of global API demand.

Key market drivers include the growing global prevalence of type 2 diabetes, driven by aging populations, sedentary lifestyles, and dietary changes, particularly in developing countries. Increasing healthcare access in emerging economies continues to expand the patient base for metformin-based therapies. Moreover, the widespread acceptance of metformin as the cornerstone of diabetes management by international guidelines ensures consistent demand. Additional drivers include its applications beyond diabetes, such as polycystic ovary syndrome (PCOS) treatment and research into potential uses in aging-related conditions and oncology, which further broaden its clinical relevance. Despite competitive pricing pressure and low margins, its indispensable role in diabetes care secures long-term market stability.
This report aims to provide a comprehensive presentation of the global market for Metformin Hydrochloride, focusing on the total sales volume, sales revenue, price, key companies market share and ranking, together with an analysis of Metformin Hydrochloride by region & country, by Type, and by Application.
The Metformin Hydrochloride market size, estimations, and forecasts are provided in terms of sales volume (MT) and sales revenue ($ millions), considering 2024 as the base year, with history and forecast data for the period from 2020 to 2031. With both quantitative and qualitative analysis, to help readers develop business/growth strategies, assess the market competitive situation, analyze their position in the current marketplace, and make informed business decisions regarding Metformin Hydrochloride.

Market Segmentation
By Company
Wanbury
USV
Shouguang Fukang Pharmaceutical
Vistin Pharma
Ningxia Hengkang Technology
Keyuan Pharmaceutical
FARMHISPANIA GROUP
Harman Finochem
Shijiazhuang Polee Pharmaceutical
Aarti Drugs
Exemed Pharmaceuticals
Granules
Segment by Type
Metformin HCL
Metformin DC
Segment by Application
Metformin Hydrochloride Tablets
Metformin Hydrochloride Extended-Release Tablets
Others
By Region
North America
United States
Canada
Asia-Pacific
China
Japan
South Korea
Southeast Asia
India
Australia
Rest of Asia-Pacific
Europe
Germany
France
U.K.
Italy
Netherlands
Nordic Countries
Rest of Europe
Latin America
Mexico
Brazil
Rest of Latin America
Middle East & Africa
Turkey
Saudi Arabia
UAE
Rest of MEA
Chapter Outline
Chapter 1: Introduces the report scope of the report, global total market size (value, volume and price). This chapter also provides the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter 2: Detailed analysis of Metformin Hydrochloride manufacturers competitive landscape, price, sales and revenue market share, latest development plan, merger, and acquisition information, etc.
Chapter 3: Provides the analysis of various market segments by Type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter 4: Provides the analysis of various market segments by Application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter 5: Sales, revenue of Metformin Hydrochloride in regional level. It provides a quantitative analysis of the market size and development potential of each region and introduces the market development, future development prospects, market space, and market size of each country in the world.
Chapter 6: Sales, revenue of Metformin Hydrochloride in country level. It provides sigmate data by Type, and by Application for each country/region.
Chapter 7: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product sales, revenue, price, gross margin, product introduction, recent development, etc.
Chapter 8: Analysis of industrial chain, including the upstream and downstream of the industry.
Chapter 9: Conclusion.

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Table of Contents

1 Market Overview
1.1 Metformin Hydrochloride Product Introduction
1.2 Global Metformin Hydrochloride Market Size Forecast
1.2.1 Global Metformin Hydrochloride Sales Value (2020-2031)
1.2.2 Global Metformin Hydrochloride Sales Volume (2020-2031)
1.2.3 Global Metformin Hydrochloride Sales Price (2020-2031)
1.3 Metformin Hydrochloride Market Trends & Drivers
1.3.1 Metformin Hydrochloride Industry Trends
1.3.2 Metformin Hydrochloride Market Drivers & Opportunity
1.3.3 Metformin Hydrochloride Market Challenges
1.3.4 Metformin Hydrochloride Market Restraints
1.4 Assumptions and Limitations
1.5 Study Objectives
1.6 Years Considered
2 Competitive Analysis by Company
2.1 Global Metformin Hydrochloride Players Revenue Ranking (2024)
2.2 Global Metformin Hydrochloride Revenue by Company (2020-2025)
2.3 Global Metformin Hydrochloride Players Sales Volume Ranking (2024)
2.4 Global Metformin Hydrochloride Sales Volume by Company Players (2020-2025)
2.5 Global Metformin Hydrochloride Average Price by Company (2020-2025)
2.6 Key Manufacturers Metformin Hydrochloride Manufacturing Base and Headquarters
2.7 Key Manufacturers Metformin Hydrochloride Product Offered
2.8 Key Manufacturers Time to Begin Mass Production of Metformin Hydrochloride
2.9 Metformin Hydrochloride Market Competitive Analysis
2.9.1 Metformin Hydrochloride Market Concentration Rate (2020-2025)
2.9.2 Global 5 and 10 Largest Manufacturers by Metformin Hydrochloride Revenue in 2024
2.9.3 Global Top Manufacturers by Company Type (Tier 1, Tier 2, and Tier 3) & (based on the Revenue in Metformin Hydrochloride as of 2024)
2.10 Mergers & Acquisitions, Expansion
3 Segmentation by Type
3.1 Introduction by Type
3.1.1 Metformin HCL
3.1.2 Metformin DC
3.2 Global Metformin Hydrochloride Sales Value by Type
3.2.1 Global Metformin Hydrochloride Sales Value by Type (2020 VS 2024 VS 2031)
3.2.2 Global Metformin Hydrochloride Sales Value, by Type (2020-2031)
3.2.3 Global Metformin Hydrochloride Sales Value, by Type (%) (2020-2031)
3.3 Global Metformin Hydrochloride Sales Volume by Type
3.3.1 Global Metformin Hydrochloride Sales Volume by Type (2020 VS 2024 VS 2031)
3.3.2 Global Metformin Hydrochloride Sales Volume, by Type (2020-2031)
3.3.3 Global Metformin Hydrochloride Sales Volume, by Type (%) (2020-2031)
3.4 Global Metformin Hydrochloride Average Price by Type (2020-2031)
4 Segmentation by Application
4.1 Introduction by Application
4.1.1 Metformin Hydrochloride Tablets
4.1.2 Metformin Hydrochloride Extended-Release Tablets
4.1.3 Others
4.2 Global Metformin Hydrochloride Sales Value by Application
4.2.1 Global Metformin Hydrochloride Sales Value by Application (2020 VS 2024 VS 2031)
4.2.2 Global Metformin Hydrochloride Sales Value, by Application (2020-2031)
4.2.3 Global Metformin Hydrochloride Sales Value, by Application (%) (2020-2031)
4.3 Global Metformin Hydrochloride Sales Volume by Application
4.3.1 Global Metformin Hydrochloride Sales Volume by Application (2020 VS 2024 VS 2031)
4.3.2 Global Metformin Hydrochloride Sales Volume, by Application (2020-2031)
4.3.3 Global Metformin Hydrochloride Sales Volume, by Application (%) (2020-2031)
4.4 Global Metformin Hydrochloride Average Price by Application (2020-2031)
5 Segmentation by Region
5.1 Global Metformin Hydrochloride Sales Value by Region
5.1.1 Global Metformin Hydrochloride Sales Value by Region: 2020 VS 2024 VS 2031
5.1.2 Global Metformin Hydrochloride Sales Value by Region (2020-2025)
5.1.3 Global Metformin Hydrochloride Sales Value by Region (2026-2031)
5.1.4 Global Metformin Hydrochloride Sales Value by Region (%), (2020-2031)
5.2 Global Metformin Hydrochloride Sales Volume by Region
5.2.1 Global Metformin Hydrochloride Sales Volume by Region: 2020 VS 2024 VS 2031
5.2.2 Global Metformin Hydrochloride Sales Volume by Region (2020-2025)
5.2.3 Global Metformin Hydrochloride Sales Volume by Region (2026-2031)
5.2.4 Global Metformin Hydrochloride Sales Volume by Region (%), (2020-2031)
5.3 Global Metformin Hydrochloride Average Price by Region (2020-2031)
5.4 North America
5.4.1 North America Metformin Hydrochloride Sales Value, 2020-2031
5.4.2 North America Metformin Hydrochloride Sales Value by Country (%), 2024 VS 2031
5.5 Europe
5.5.1 Europe Metformin Hydrochloride Sales Value, 2020-2031
5.5.2 Europe Metformin Hydrochloride Sales Value by Country (%), 2024 VS 2031
5.6 Asia Pacific
5.6.1 Asia Pacific Metformin Hydrochloride Sales Value, 2020-2031
5.6.2 Asia Pacific Metformin Hydrochloride Sales Value by Region (%), 2024 VS 2031
5.7 South America
5.7.1 South America Metformin Hydrochloride Sales Value, 2020-2031
5.7.2 South America Metformin Hydrochloride Sales Value by Country (%), 2024 VS 2031
5.8 Middle East & Africa
5.8.1 Middle East & Africa Metformin Hydrochloride Sales Value, 2020-2031
5.8.2 Middle East & Africa Metformin Hydrochloride Sales Value by Country (%), 2024 VS 2031
6 Segmentation by Key Countries/Regions
6.1 Key Countries/Regions Metformin Hydrochloride Sales Value Growth Trends, 2020 VS 2024 VS 2031
6.2 Key Countries/Regions Metformin Hydrochloride Sales Value and Sales Volume
6.2.1 Key Countries/Regions Metformin Hydrochloride Sales Value, 2020-2031
6.2.2 Key Countries/Regions Metformin Hydrochloride Sales Volume, 2020-2031
6.3 United States
6.3.1 United States Metformin Hydrochloride Sales Value, 2020-2031
6.3.2 United States Metformin Hydrochloride Sales Value by Type (%), 2024 VS 2031
6.3.3 United States Metformin Hydrochloride Sales Value by Application, 2024 VS 2031
6.4 Europe
6.4.1 Europe Metformin Hydrochloride Sales Value, 2020-2031
6.4.2 Europe Metformin Hydrochloride Sales Value by Type (%), 2024 VS 2031
6.4.3 Europe Metformin Hydrochloride Sales Value by Application, 2024 VS 2031
6.5 China
6.5.1 China Metformin Hydrochloride Sales Value, 2020-2031
6.5.2 China Metformin Hydrochloride Sales Value by Type (%), 2024 VS 2031
6.5.3 China Metformin Hydrochloride Sales Value by Application, 2024 VS 2031
6.6 Japan
6.6.1 Japan Metformin Hydrochloride Sales Value, 2020-2031
6.6.2 Japan Metformin Hydrochloride Sales Value by Type (%), 2024 VS 2031
6.6.3 Japan Metformin Hydrochloride Sales Value by Application, 2024 VS 2031
6.7 South Korea
6.7.1 South Korea Metformin Hydrochloride Sales Value, 2020-2031
6.7.2 South Korea Metformin Hydrochloride Sales Value by Type (%), 2024 VS 2031
6.7.3 South Korea Metformin Hydrochloride Sales Value by Application, 2024 VS 2031
6.8 Southeast Asia
6.8.1 Southeast Asia Metformin Hydrochloride Sales Value, 2020-2031
6.8.2 Southeast Asia Metformin Hydrochloride Sales Value by Type (%), 2024 VS 2031
6.8.3 Southeast Asia Metformin Hydrochloride Sales Value by Application, 2024 VS 2031
6.9 India
6.9.1 India Metformin Hydrochloride Sales Value, 2020-2031
6.9.2 India Metformin Hydrochloride Sales Value by Type (%), 2024 VS 2031
6.9.3 India Metformin Hydrochloride Sales Value by Application, 2024 VS 2031
7 Company Profiles
7.1 Wanbury
7.1.1 Wanbury Company Information
7.1.2 Wanbury Introduction and Business Overview
7.1.3 Wanbury Metformin Hydrochloride Sales, Revenue, Price and Gross Margin (2020-2025)
7.1.4 Wanbury Metformin Hydrochloride Product Offerings
7.1.5 Wanbury Recent Development
7.2 USV
7.2.1 USV Company Information
7.2.2 USV Introduction and Business Overview
7.2.3 USV Metformin Hydrochloride Sales, Revenue, Price and Gross Margin (2020-2025)
7.2.4 USV Metformin Hydrochloride Product Offerings
7.2.5 USV Recent Development
7.3 Shouguang Fukang Pharmaceutical
7.3.1 Shouguang Fukang Pharmaceutical Company Information
7.3.2 Shouguang Fukang Pharmaceutical Introduction and Business Overview
7.3.3 Shouguang Fukang Pharmaceutical Metformin Hydrochloride Sales, Revenue, Price and Gross Margin (2020-2025)
7.3.4 Shouguang Fukang Pharmaceutical Metformin Hydrochloride Product Offerings
7.3.5 Shouguang Fukang Pharmaceutical Recent Development
7.4 Vistin Pharma
7.4.1 Vistin Pharma Company Information
7.4.2 Vistin Pharma Introduction and Business Overview
7.4.3 Vistin Pharma Metformin Hydrochloride Sales, Revenue, Price and Gross Margin (2020-2025)
7.4.4 Vistin Pharma Metformin Hydrochloride Product Offerings
7.4.5 Vistin Pharma Recent Development
7.5 Ningxia Hengkang Technology
7.5.1 Ningxia Hengkang Technology Company Information
7.5.2 Ningxia Hengkang Technology Introduction and Business Overview
7.5.3 Ningxia Hengkang Technology Metformin Hydrochloride Sales, Revenue, Price and Gross Margin (2020-2025)
7.5.4 Ningxia Hengkang Technology Metformin Hydrochloride Product Offerings
7.5.5 Ningxia Hengkang Technology Recent Development
7.6 Keyuan Pharmaceutical
7.6.1 Keyuan Pharmaceutical Company Information
7.6.2 Keyuan Pharmaceutical Introduction and Business Overview
7.6.3 Keyuan Pharmaceutical Metformin Hydrochloride Sales, Revenue, Price and Gross Margin (2020-2025)
7.6.4 Keyuan Pharmaceutical Metformin Hydrochloride Product Offerings
7.6.5 Keyuan Pharmaceutical Recent Development
7.7 FARMHISPANIA GROUP
7.7.1 FARMHISPANIA GROUP Company Information
7.7.2 FARMHISPANIA GROUP Introduction and Business Overview
7.7.3 FARMHISPANIA GROUP Metformin Hydrochloride Sales, Revenue, Price and Gross Margin (2020-2025)
7.7.4 FARMHISPANIA GROUP Metformin Hydrochloride Product Offerings
7.7.5 FARMHISPANIA GROUP Recent Development
7.8 Harman Finochem
7.8.1 Harman Finochem Company Information
7.8.2 Harman Finochem Introduction and Business Overview
7.8.3 Harman Finochem Metformin Hydrochloride Sales, Revenue, Price and Gross Margin (2020-2025)
7.8.4 Harman Finochem Metformin Hydrochloride Product Offerings
7.8.5 Harman Finochem Recent Development
7.9 Shijiazhuang Polee Pharmaceutical
7.9.1 Shijiazhuang Polee Pharmaceutical Company Information
7.9.2 Shijiazhuang Polee Pharmaceutical Introduction and Business Overview
7.9.3 Shijiazhuang Polee Pharmaceutical Metformin Hydrochloride Sales, Revenue, Price and Gross Margin (2020-2025)
7.9.4 Shijiazhuang Polee Pharmaceutical Metformin Hydrochloride Product Offerings
7.9.5 Shijiazhuang Polee Pharmaceutical Recent Development
7.10 Aarti Drugs
7.10.1 Aarti Drugs Company Information
7.10.2 Aarti Drugs Introduction and Business Overview
7.10.3 Aarti Drugs Metformin Hydrochloride Sales, Revenue, Price and Gross Margin (2020-2025)
7.10.4 Aarti Drugs Metformin Hydrochloride Product Offerings
7.10.5 Aarti Drugs Recent Development
7.11 Exemed Pharmaceuticals
7.11.1 Exemed Pharmaceuticals Company Information
7.11.2 Exemed Pharmaceuticals Introduction and Business Overview
7.11.3 Exemed Pharmaceuticals Metformin Hydrochloride Sales, Revenue, Price and Gross Margin (2020-2025)
7.11.4 Exemed Pharmaceuticals Metformin Hydrochloride Product Offerings
7.11.5 Exemed Pharmaceuticals Recent Development
7.12 Granules
7.12.1 Granules Company Information
7.12.2 Granules Introduction and Business Overview
7.12.3 Granules Metformin Hydrochloride Sales, Revenue, Price and Gross Margin (2020-2025)
7.12.4 Granules Metformin Hydrochloride Product Offerings
7.12.5 Granules Recent Development
8 Industry Chain Analysis
8.1 Metformin Hydrochloride Industrial Chain
8.2 Metformin Hydrochloride Upstream Analysis
8.2.1 Key Raw Materials
8.2.2 Raw Materials Key Suppliers
8.2.3 Manufacturing Cost Structure
8.3 Midstream Analysis
8.4 Downstream Analysis (Customers Analysis)
8.5 Sales Model and Sales Channels
8.5.1 Metformin Hydrochloride Sales Model
8.5.2 Sales Channel
8.5.3 Metformin Hydrochloride Distributors
9 Research Findings and Conclusion
10 Appendix
10.1 Research Methodology
10.1.1 Methodology/Research Approach
10.1.1.1 Research Programs/Design
10.1.1.2 Market Size Estimation
10.1.1.3 Market Breakdown and Data Triangulation
10.1.2 Data Source
10.1.2.1 Secondary Sources
10.1.2.2 Primary Sources
10.2 Author Details
10.3 Disclaimer