Summary

The global market for FIB-SEM System was estimated to be worth US$ 626 million in 2024 and is forecast to a readjusted size of US$ 919 million by 2031 with a CAGR of 5.7% during the forecast period 2025-2031.
The FIB-SEM system is an electron microscope system that integrates focused electron beams and scanning ion beams. Focused ion beams can be used for micro processing of samples, scanning electron beams can be used for micro imaging and "two-dimensional" characterization analysis of sample surface morphology, and real-time observation of the FIB processing process. Therefore, the FIB-SEM system can achieve fixed-point etching, deposition, cross-sectional cutting, TEM electron microscopy sample preparation, and micro/nano device preparation of samples Circuit repair, 3D structural characterization, etc.
Global key players of FIB-SEM System include Thermo Fisher Scientific Hitachi and Zeiss, etc. The top three players hold a share over 85%. Japan is the largest market. In terms of product type, Ga Ion Source is the largest segment, occupied for a share of 95%, and in terms of application, Material Science has a share about 40 percent.
Analysis of FIB-SEM system market drivers
1. Demand for semiconductor technology iteration
Advanced process node promotion:
3nm/2nm chip process requires atomic-level defect detection, and FIB-SEM supports nanoscale circuit editing and material composition analysis (such as EDS/EBSD integration) to help improve yield.
3D packaging technology (such as Chiplet) relies on FIB-SEM for through-silicon via (TSV) cross-sectional analysis and interface defect positioning.
Semiconductor material innovation:
The microstructure research of third-generation semiconductors (GaN, SiC) and two-dimensional materials (graphene) requires FIB-SEM to achieve atomic-level resolution imaging (＜0.5nm).
2. Biomedical and life science research
Tissue engineering and drug delivery:
FIB-SEM supports cell-material interface imaging, analyzes the distribution of nanoparticles in the body, and accelerates targeted drug development.
Brain neuroscience: 3D reconstruction of the whole brain neural network is achieved through volume electron microscopy (SBEM), promoting the study of the mechanism of neurodegenerative diseases.
Implantable medical devices:
Analysis of nanoscale surface morphology of biocompatible materials (such as degradable stents) to optimize device design.
3. Breakthroughs in materials science
Research and development of new energy materials:
Study on the growth mechanism of lithium dendrites in solid-state batteries requires FIB-SEM combined with low-temperature in-situ electron microscopy technology.
Analysis of hydrogen embrittlement: Observation of metal microscopic crack propagation in transmission electron microscope samples prepared by FIB.
Design of nanocomposite materials:
FIB-SEM supports 3D structural characterization of multimodal materials (such as graphene/metal composites) to help optimize performance.
4. Industry 4.0 and smart manufacturing
Micro-nano manufacturing upgrade:
The complex structure processing of MEMS sensors (such as inertial measurement units) relies on the ion beam direct writing technology of FIB-SEM.
Nanoscale circuit repair of flexible electronics (such as foldable screens) drives the growth of equipment demand.
Intelligent quality control:
AI integrated FIB-SEM system realizes automated defect detection (such as wafer surface particle analysis) to improve production line efficiency.
5. Academic and policy support
Research funding:
Global nanotechnology R&D investment increased by 8% annually (NSF data), and universities/national laboratories purchased FIB-SEM for cutting-edge exploration.
China's "14th Five-Year Plan" focuses on supporting the localization of electron microscopes, giving rise to local equipment demand.
Open source science trends:
FIB-SEM data sharing platforms (such as EMPIAR) promote interdisciplinary cooperation and accelerate technology popularization.
6. Technology integration and innovation
Multimodal combined technology:
FIB-SEM is integrated with Raman spectroscopy/AFM to achieve morphology-composition-mechanics multi-attribute correlation analysis.
In-situ electrical testing: Directly measure carrier transport characteristics on FIB-prepared nanostructures.
AI-assisted analysis:
Deep learning algorithms increase FIB-SEM imaging speed by 3-5 times and reduce the operating threshold.
Market growth forecast and competition focus.
Decisive factors:
Resolution and processing accuracy: Breakthrough to sub-nanometer level (＜0.3nm) to support quantum material research.
Automation and data ecology: Develop AI-driven full-process solutions (such as sample preparation-imaging-analysis integration).
Summary: The three core driving forces of semiconductor technology generational evolution, biomedical interdisciplinary integration, and material science paradigm innovation, coupled with policy support and AI technology empowerment, promote FIB-SEM from a scientific research tool to an industrial standard. Chinese companies need to break through the bottlenecks of ion source stability and software algorithms to seize the high-end market.
This report aims to provide a comprehensive presentation of the global market for FIB-SEM System, focusing on the total sales volume, sales revenue, price, key companies market share and ranking, together with an analysis of FIB-SEM System by region & country, by Type, and by Application.
The FIB-SEM System market size, estimations, and forecasts are provided in terms of sales volume (Units) and sales revenue ($ millions), considering 2024 as the base year, with history and forecast data for the period from 2020 to 2031. With both quantitative and qualitative analysis, to help readers develop business/growth strategies, assess the market competitive situation, analyze their position in the current marketplace, and make informed business decisions regarding FIB-SEM System.
Market Segmentation
By Company
Thermo Fisher Scientific
Hitachi
Zeiss
JEOL Ltd
Tescan Group
Raith
Segment by Type
Ga Ion Source
Non-Ga Ion Source
Segment by Application
Material Science
Life Sciences
Semiconductor
By Region
North America
United States
Canada
Asia-Pacific
China
Japan
South Korea
Southeast Asia
India
Australia
Rest of Asia-Pacific
Europe
Germany
France
U.K.
Italy
Netherlands
Nordic Countries
Rest of Europe
Latin America
Mexico
Brazil
Rest of Latin America
Middle East & Africa
Turkey
Saudi Arabia
UAE
Rest of MEA
Chapter Outline
Chapter 1: Introduces the report scope of the report, global total market size (value, volume and price). This chapter also provides the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter 2: Detailed analysis of FIB-SEM System manufacturers competitive landscape, price, sales and revenue market share, latest development plan, merger, and acquisition information, etc.
Chapter 3: Provides the analysis of various market segments by Type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter 4: Provides the analysis of various market segments by Application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter 5: Sales, revenue of FIB-SEM System in regional level. It provides a quantitative analysis of the market size and development potential of each region and introduces the market development, future development prospects, market space, and market size of each country in the world.
Chapter 6: Sales, revenue of FIB-SEM System in country level. It provides sigmate data by Type, and by Application for each country/region.
Chapter 7: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product sales, revenue, price, gross margin, product introduction, recent development, etc.
Chapter 8: Analysis of industrial chain, including the upstream and downstream of the industry.
Chapter 9: Conclusion.

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Table of Contents

1 Market Overview
1.1 FIB-SEM System Product Introduction
1.2 Global FIB-SEM System Market Size Forecast
1.2.1 Global FIB-SEM System Sales Value (2020-2031)
1.2.2 Global FIB-SEM System Sales Volume (2020-2031)
1.2.3 Global FIB-SEM System Sales Price (2020-2031)
1.3 FIB-SEM System Market Trends & Drivers
1.3.1 FIB-SEM System Industry Trends
1.3.2 FIB-SEM System Market Drivers & Opportunity
1.3.3 FIB-SEM System Market Challenges
1.3.4 FIB-SEM System Market Restraints
1.4 Assumptions and Limitations
1.5 Study Objectives
1.6 Years Considered
2 Competitive Analysis by Company
2.1 Global FIB-SEM System Players Revenue Ranking (2024)
2.2 Global FIB-SEM System Revenue by Company (2020-2025)
2.3 Global FIB-SEM System Players Sales Volume Ranking (2024)
2.4 Global FIB-SEM System Sales Volume by Company Players (2020-2025)
2.5 Global FIB-SEM System Average Price by Company (2020-2025)
2.6 Key Manufacturers FIB-SEM System Manufacturing Base and Headquarters
2.7 Key Manufacturers FIB-SEM System Product Offered
2.8 Key Manufacturers Time to Begin Mass Production of FIB-SEM System
2.9 FIB-SEM System Market Competitive Analysis
2.9.1 FIB-SEM System Market Concentration Rate (2020-2025)
2.9.2 Global 5 and 10 Largest Manufacturers by FIB-SEM System Revenue in 2024
2.9.3 Global Top Manufacturers by Company Type (Tier 1, Tier 2, and Tier 3) & (based on the Revenue in FIB-SEM System as of 2024)
2.10 Mergers & Acquisitions, Expansion
3 Segmentation by Type
3.1 Introduction by Type
3.1.1 Ga Ion Source
3.1.2 Non-Ga Ion Source
3.2 Global FIB-SEM System Sales Value by Type
3.2.1 Global FIB-SEM System Sales Value by Type (2020 VS 2024 VS 2031)
3.2.2 Global FIB-SEM System Sales Value, by Type (2020-2031)
3.2.3 Global FIB-SEM System Sales Value, by Type (%) (2020-2031)
3.3 Global FIB-SEM System Sales Volume by Type
3.3.1 Global FIB-SEM System Sales Volume by Type (2020 VS 2024 VS 2031)
3.3.2 Global FIB-SEM System Sales Volume, by Type (2020-2031)
3.3.3 Global FIB-SEM System Sales Volume, by Type (%) (2020-2031)
3.4 Global FIB-SEM System Average Price by Type (2020-2031)
4 Segmentation by Application
4.1 Introduction by Application
4.1.1 Material Science
4.1.2 Life Sciences
4.1.3 Semiconductor
4.2 Global FIB-SEM System Sales Value by Application
4.2.1 Global FIB-SEM System Sales Value by Application (2020 VS 2024 VS 2031)
4.2.2 Global FIB-SEM System Sales Value, by Application (2020-2031)
4.2.3 Global FIB-SEM System Sales Value, by Application (%) (2020-2031)
4.3 Global FIB-SEM System Sales Volume by Application
4.3.1 Global FIB-SEM System Sales Volume by Application (2020 VS 2024 VS 2031)
4.3.2 Global FIB-SEM System Sales Volume, by Application (2020-2031)
4.3.3 Global FIB-SEM System Sales Volume, by Application (%) (2020-2031)
4.4 Global FIB-SEM System Average Price by Application (2020-2031)
5 Segmentation by Region
5.1 Global FIB-SEM System Sales Value by Region
5.1.1 Global FIB-SEM System Sales Value by Region: 2020 VS 2024 VS 2031
5.1.2 Global FIB-SEM System Sales Value by Region (2020-2025)
5.1.3 Global FIB-SEM System Sales Value by Region (2026-2031)
5.1.4 Global FIB-SEM System Sales Value by Region (%), (2020-2031)
5.2 Global FIB-SEM System Sales Volume by Region
5.2.1 Global FIB-SEM System Sales Volume by Region: 2020 VS 2024 VS 2031
5.2.2 Global FIB-SEM System Sales Volume by Region (2020-2025)
5.2.3 Global FIB-SEM System Sales Volume by Region (2026-2031)
5.2.4 Global FIB-SEM System Sales Volume by Region (%), (2020-2031)
5.3 Global FIB-SEM System Average Price by Region (2020-2031)
5.4 North America
5.4.1 North America FIB-SEM System Sales Value, 2020-2031
5.4.2 North America FIB-SEM System Sales Value by Country (%), 2024 VS 2031
5.5 Europe
5.5.1 Europe FIB-SEM System Sales Value, 2020-2031
5.5.2 Europe FIB-SEM System Sales Value by Country (%), 2024 VS 2031
5.6 Asia Pacific
5.6.1 Asia Pacific FIB-SEM System Sales Value, 2020-2031
5.6.2 Asia Pacific FIB-SEM System Sales Value by Region (%), 2024 VS 2031
5.7 South America
5.7.1 South America FIB-SEM System Sales Value, 2020-2031
5.7.2 South America FIB-SEM System Sales Value by Country (%), 2024 VS 2031
5.8 Middle East & Africa
5.8.1 Middle East & Africa FIB-SEM System Sales Value, 2020-2031
5.8.2 Middle East & Africa FIB-SEM System Sales Value by Country (%), 2024 VS 2031
6 Segmentation by Key Countries/Regions
6.1 Key Countries/Regions FIB-SEM System Sales Value Growth Trends, 2020 VS 2024 VS 2031
6.2 Key Countries/Regions FIB-SEM System Sales Value and Sales Volume
6.2.1 Key Countries/Regions FIB-SEM System Sales Value, 2020-2031
6.2.2 Key Countries/Regions FIB-SEM System Sales Volume, 2020-2031
6.3 United States
6.3.1 United States FIB-SEM System Sales Value, 2020-2031
6.3.2 United States FIB-SEM System Sales Value by Type (%), 2024 VS 2031
6.3.3 United States FIB-SEM System Sales Value by Application, 2024 VS 2031
6.4 Europe
6.4.1 Europe FIB-SEM System Sales Value, 2020-2031
6.4.2 Europe FIB-SEM System Sales Value by Type (%), 2024 VS 2031
6.4.3 Europe FIB-SEM System Sales Value by Application, 2024 VS 2031
6.5 China
6.5.1 China FIB-SEM System Sales Value, 2020-2031
6.5.2 China FIB-SEM System Sales Value by Type (%), 2024 VS 2031
6.5.3 China FIB-SEM System Sales Value by Application, 2024 VS 2031
6.6 Japan
6.6.1 Japan FIB-SEM System Sales Value, 2020-2031
6.6.2 Japan FIB-SEM System Sales Value by Type (%), 2024 VS 2031
6.6.3 Japan FIB-SEM System Sales Value by Application, 2024 VS 2031
6.7 South Korea
6.7.1 South Korea FIB-SEM System Sales Value, 2020-2031
6.7.2 South Korea FIB-SEM System Sales Value by Type (%), 2024 VS 2031
6.7.3 South Korea FIB-SEM System Sales Value by Application, 2024 VS 2031
6.8 Southeast Asia
6.8.1 Southeast Asia FIB-SEM System Sales Value, 2020-2031
6.8.2 Southeast Asia FIB-SEM System Sales Value by Type (%), 2024 VS 2031
6.8.3 Southeast Asia FIB-SEM System Sales Value by Application, 2024 VS 2031
6.9 India
6.9.1 India FIB-SEM System Sales Value, 2020-2031
6.9.2 India FIB-SEM System Sales Value by Type (%), 2024 VS 2031
6.9.3 India FIB-SEM System Sales Value by Application, 2024 VS 2031
7 Company Profiles
7.1 Thermo Fisher Scientific
7.1.1 Thermo Fisher Scientific Company Information
7.1.2 Thermo Fisher Scientific Introduction and Business Overview
7.1.3 Thermo Fisher Scientific FIB-SEM System Sales, Revenue, Price and Gross Margin (2020-2025)
7.1.4 Thermo Fisher Scientific FIB-SEM System Product Offerings
7.1.5 Thermo Fisher Scientific Recent Development
7.2 Hitachi
7.2.1 Hitachi Company Information
7.2.2 Hitachi Introduction and Business Overview
7.2.3 Hitachi FIB-SEM System Sales, Revenue, Price and Gross Margin (2020-2025)
7.2.4 Hitachi FIB-SEM System Product Offerings
7.2.5 Hitachi Recent Development
7.3 Zeiss
7.3.1 Zeiss Company Information
7.3.2 Zeiss Introduction and Business Overview
7.3.3 Zeiss FIB-SEM System Sales, Revenue, Price and Gross Margin (2020-2025)
7.3.4 Zeiss FIB-SEM System Product Offerings
7.3.5 Zeiss Recent Development
7.4 JEOL Ltd
7.4.1 JEOL Ltd Company Information
7.4.2 JEOL Ltd Introduction and Business Overview
7.4.3 JEOL Ltd FIB-SEM System Sales, Revenue, Price and Gross Margin (2020-2025)
7.4.4 JEOL Ltd FIB-SEM System Product Offerings
7.4.5 JEOL Ltd Recent Development
7.5 Tescan Group
7.5.1 Tescan Group Company Information
7.5.2 Tescan Group Introduction and Business Overview
7.5.3 Tescan Group FIB-SEM System Sales, Revenue, Price and Gross Margin (2020-2025)
7.5.4 Tescan Group FIB-SEM System Product Offerings
7.5.5 Tescan Group Recent Development
7.6 Raith
7.6.1 Raith Company Information
7.6.2 Raith Introduction and Business Overview
7.6.3 Raith FIB-SEM System Sales, Revenue, Price and Gross Margin (2020-2025)
7.6.4 Raith FIB-SEM System Product Offerings
7.6.5 Raith Recent Development
8 Industry Chain Analysis
8.1 FIB-SEM System Industrial Chain
8.2 FIB-SEM System Upstream Analysis
8.2.1 Key Raw Materials
8.2.2 Raw Materials Key Suppliers
8.2.3 Manufacturing Cost Structure
8.3 Midstream Analysis
8.4 Downstream Analysis (Customers Analysis)
8.5 Sales Model and Sales Channels
8.5.1 FIB-SEM System Sales Model
8.5.2 Sales Channel
8.5.3 FIB-SEM System Distributors
9 Research Findings and Conclusion
10 Appendix
10.1 Research Methodology
10.1.1 Methodology/Research Approach
10.1.1.1 Research Programs/Design
10.1.1.2 Market Size Estimation
10.1.1.3 Market Breakdown and Data Triangulation
10.1.2 Data Source
10.1.2.1 Secondary Sources
10.1.2.2 Primary Sources
10.2 Author Details
10.3 Disclaimer