Summary

U.S. Healthcare Information System Market Summary

The U.S. healthcare information systems market size was estimated at USD 238.45 billion in 2024 and is projected to reach USD 678.39 billion by 2033, growing at a CAGR of 12.40% from 2025 to 2033. The increasing prevalence of chronic diseases in the country is driving the adoption of remote patient monitoring. This growing trend is anticipated to enhance the demand for IT solutions within the healthcare industry in the U.S. In addition, the industry is expected to experience growth driven by several advantages, including operational cost reductions, a decrease in medical errors, and enhanced patient outcomes. Moreover, supportive government initiatives aimed at developing healthcare infrastructure and integrating IT solutions into existing facilities are anticipated to further stimulate industry expansion during the forecast period.

The push for interoperability is a key driver in the U.S. healthcare information systems market. Providers, payers, and patients require seamless access to data across different systems to support care coordination. Regulations under the 21st Century Cures Act mandate the elimination of information blocking, further accelerating the need for interoperable platforms. Systems that enable data exchange between hospitals, diagnostic centers, ambulatory care, and insurers are becoming essential. Such regulatory and operational demand is driving upgrades to existing healthcare IT infrastructures. For instance, in August 2025, Epic unveiled significant artificial intelligence (AI) features integrated into its electronic health record (EHR) platform, including AI-assisted charting to streamline documentation, Microsoft’s Cosmos AI for enhanced risk prediction, and revenue cycle management (RCM) improvements. These advancements aim to boost clinical efficiency, optimize patient care, and improve financial workflows for healthcare providers.

U.S. Healthcare Information Systems Market Report Segmentation

This report forecasts revenue growth at country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, Grand View Research has segmented U.S. healthcare information systems market report based on application, deployment mode, component, and end use.
• Application Outlook (Revenue, USD Million, 2021 - 2033)
• Hospital Information System
o Electronic Health Record
o Electronic Medical Record
o Real-time Healthcare
o Patient Engagement Solution
o Population Health Management
• Pharmacy Automation Systems
o Medication Dispensing System
o Packaging & Labeling System
o Storage & Retrieval System
o Automated Medication Compounding System
o Tabletop Tablet Counters
• Laboratory Informatics
• Revenue Cycle Management
• Medical Imaging Information System
o Radiology Information Systems
o Monitoring Analysis Software
o Picture Archiving and Communication Systems
• Deployment Outlook (Revenue, USD Million, 2021 - 2033)
• Web-based
• On-premises
• Cloud-based
• Component Outlook (Revenue, USD Million, 2021 - 2033)
• Hardware
• Software & Systems
• Services
• End Use Outlook (Revenue, USD Million, 2021 - 2033)
• Hospitals & Ambulatory Services
• Diagnostic Centers
• Academic And Research Institutes

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Table of Contents

Table of Contents

Chapter 1. Methodology and Scope
1.1. Market Segmentation & Scope
1.2. Market Definitions
1.2.1. Application Segment
1.2.2. Deployment Segment
1.2.3. Component Segment
1.2.4. End Use
1.3. Information analysis
1.3.1. Market formulation & data visualization
1.4. Data validation & publishing
1.5. Information Procurement
1.5.1. Primary Research
1.6. Information or Data Analysis
1.7. Market Formulation & Validation
1.8. Market Model
1.9. Total Market: CAGR Calculation
1.10. Objectives
1.10.1. Objective 1
1.10.2. Objective 2
Chapter 2. Executive Summary
2.1. Market Outlook
2.2. Segment Snapshot
2.3. Competitive Insights Landscape
Chapter 3. U.S. Healthcare Information Systems Market Variables, Trends & Scope
3.1. Market Lineage Outlook
3.1.1. Parent market outlook
3.1.2. Related/ancillary market outlook.
3.2. Market Dynamics
3.2.1. Market driver analysis
3.2.1.1. Rising prevalence of hypertension and cardiovascular diseases
3.2.1.2. Increasing demand for continuous and non-invasive monitoring
3.2.1.3. Advancements in AI and sensor technologies and growing consumer adoption of smart health devices
3.2.2. Market restraint analysis
3.2.2.1. Data security and privacy concerns
3.2.2.2. High costs of advanced devices
3.2.3. Market opportunity analysis
3.2.4. Market challenges analysis
3.3. U.S. Healthcare Information Systems Market Analysis Tools
3.3.1. Industry Analysis - Porter’s
3.3.1.1. Supplier power
3.3.1.2. Buyer power
3.3.1.3. Substitution threat
3.3.1.4. Threat of new entrant
3.3.1.5. Competitive rivalry
3.3.2. PESTEL Analysis
3.3.2.1. Political landscape
3.3.2.2. Technological landscape
3.3.2.3. Economic landscape
3.3.2.4. Environmental Landscape
3.3.2.5. Legal Landscape
3.3.2.6. Social Landscape
Chapter 4. U.S. Healthcare Information Systems Market: Device Type Estimates & Trend Analysis
4.1. Segment Dashboard
4.2. U.S. Healthcare Information Systems Market Device Type Movement Analysis
4.3. U.S. Healthcare Information Systems Market Size & Trend Analysis, by Device Type, 2021 to 2033 (USD Million)
4.4. Hospital Information System
4.4.1. Hospital information system market estimates and forecasts, 2021 - 2033 (USD Million)
4.4.2. Electronic Health Record
4.4.2.1. Electronic health record market estimates and forecasts, 2021 - 2033 (USD Million)
4.4.3. Electronic Medical Record
4.4.3.1. Electronic medical record market estimates and forecasts, 2021 - 2033 (USD Million)
4.4.4. Real-Time Healthcare
4.4.4.1. Real-time healthcare market estimates and forecasts, 2021 - 2033 (USD Million)
4.4.5. Patient Engagement Solution
4.4.5.1. Patient engagement solution market estimates and forecasts, 2021 - 2033 (USD Million)
4.4.6. Population Health Management
4.4.6.1. Population health management market estimates and forecasts, 2021 - 2033 (USD Million)
4.5. Pharmacy Automation Systems
4.5.1. Pharmacy automation systems market estimates and forecasts, 2021 - 2033 (USD Million)
4.5.2. Medication Dispensing System
4.5.2.1. Medication dispensing system market estimates and forecasts, 2021 - 2033 (USD Million)
4.5.3. Packaging & Labeling System
4.5.3.1. Packaging & labeling system market estimates and forecasts, 2021 - 2033 (USD Million)
4.5.4. Storage & Retrieval System
4.5.4.1. Storage & retrieval system estimates and forecasts, 2021 - 2033 (USD Million)
4.5.5. Automated Medication Compounding System
4.5.5.1. Automated medication compounding system market estimates and forecasts, 2021 - 2033 (USD Million)
4.5.6. Tabletop Tablet Counters
4.5.6.1. Tabletop tablet counters market estimates and forecasts, 2021 - 2033 (USD Million)
4.6. Laboratory Informatics
4.6.1. Laboratory informatics market estimates and forecasts, 2021 - 2033 (USD Million)
4.7. Revenue Cycle Management
4.7.1. Revenue cycle management market estimates and forecasts, 2021 - 2033 (USD Million)
4.8. Medical Imaging Information System
4.8.1. Medical imaging information system market estimates and forecasts, 2021 - 2033 (USD Million)
4.8.2. Radiology Information Systems
4.8.2.1. Radiology information systems market estimates and forecasts, 2021 - 2033 (USD Million)
4.8.3. Monitoring Analysis Software
4.8.3.1. Monitoring analysis software market estimates and forecasts, 2021 - 2033 (USD Million)
4.8.4. Picture Archiving and Communication Systems
4.8.4.1. Picture archiving and communication systems market estimates and forecasts, 2021 - 2033 (USD Million)
Chapter 5. U.S. Healthcare Information Systems Market: Deployment Estimates & Trend Analysis
5.1. Segment Dashboard
5.2. U.S. Healthcare Information Systems Market Deployment Movement Analysis
5.3. U.S. Healthcare Information Systems Market Size & Trend Analysis, by Deployment, 2021 to 2033 (USD Million)
5.4. Web-based
5.4.1. Web-based market estimates and forecasts, 2021 - 2033 (USD Million)
5.5. On-premises
5.5.1. On-premises market estimates and forecasts, 2021 - 2033 (USD Million)
5.6. Cloud-based
5.6.1. Cloud-based market estimates and forecasts, 2021 - 2033 (USD Million)
Chapter 6. U.S. Healthcare Information Systems Market: Component Estimates & Trend Analysis
6.1. Segment Dashboard
6.2. U.S. Healthcare Information Systems Market Component Movement Analysis
6.3. U.S. Healthcare Information Systems Market Size & Trend Analysis, by Component, 2021 to 2033 (USD Million)
6.4. Hardware
6.4.1. Hardware market estimates and forecasts, 2021 - 2033 (USD Million)
6.5. Software & Systems
6.5.1. Software & systems market estimates and forecasts, 2021 - 2033 (USD Million)
6.6. Services
6.6.1. Services market estimates and forecasts, 2021 - 2033 (USD Million)
Chapter 7. U.S. Healthcare Information Systems Market: End Use Estimates & Trend Analysis
7.1. Segment Dashboard
7.2. U.S. Healthcare Information Systems Market End Use Movement Analysis
7.3. U.S. Healthcare Information Systems Market Size & Trend Analysis, by End Use, 2021 to 2033 (USD Million)
7.4. Hospitals & Ambulatory Services
7.4.1. Hospitals & Ambulatory Services market estimates and forecasts, 2021 - 2033 (USD Million)
7.5. Diagnostic Centers
7.5.1. Diagnostic centers market estimates and forecasts, 2021 - 2033 (USD Million)
7.6. Academic and Research Institutes
7.6.1. Academic and research institutes market estimates and forecasts, 2021 - 2033 (USD Million)
Chapter 8. Competitive Landscape
8.1. Company/Competition Categorization
8.2. Strategy Mapping
8.3. Company Market Position Analysis, 2024
8.4. Company Profiles/Listing
8.4.1. Athenahealth Inc.
8.4.1.1. Company overview
8.4.1.2. Financial performance
8.4.1.3. Product benchmarking
8.4.1.4. Strategic initiatives
8.4.2. Change Healthcare Inc.
8.4.2.1. Company overview
8.4.2.2. Financial performance
8.4.2.3. Product benchmarking
8.4.2.4. Strategic initiatives
8.4.3. GE Healthcare
8.4.3.1. Company overview
8.4.3.2. Financial performance
8.4.3.3. Product benchmarking
8.4.3.4. Strategic initiatives
8.4.4. IBM
8.4.4.1. Company overview
8.4.4.2. Financial performance
8.4.4.3. Product benchmarking
8.4.4.4. Strategic initiatives
8.4.5. Oracle Corporation
8.4.5.1. Company overview
8.4.5.2. Financial performance
8.4.5.3. Product benchmarking
8.4.5.4. Strategic initiatives
8.4.6. Dell Technologies Inc.
8.4.6.1. Company overview
8.4.6.2. Financial performance
8.4.6.3. Product benchmarking
8.4.6.4. Strategic initiatives
8.4.7. Philips Healthcare
8.4.7.1. Company overview
8.4.7.2. Financial performance
8.4.7.3. Product benchmarking
8.4.7.4. Strategic initiatives
8.4.8. Optum
8.4.8.1. Company overview
8.4.8.2. Financial performance
8.4.8.3. Product benchmarking
8.4.8.4. Strategic initiatives
8.4.9. Infor
8.4.9.1. Company overview
8.4.9.2. Financial performance
8.4.9.3. Product benchmarking
8.4.9.4. Strategic initiatives
8.4.10. Epic Systems Corporation
8.4.10.1. Company overview
8.4.10.2. Financial performance
8.4.10.3. Product benchmarking
8.4.10.4. Strategic initiatives
8.4.11. Veradigm LLC.
8.4.11.1. Company overview
8.4.11.2. Financial performance
8.4.11.3. Product benchmarking
8.4.11.4. Strategic initiatives
8.4.12. Conduent Inc.
8.4.12.1. Company overview
8.4.12.2. Financial performance
8.4.12.3. Product benchmarking
8.4.12.4. Strategic initiatives
8.4.13. Cognizant Technology Solutions Corporation
8.4.13.1. Company overview
8.4.13.2. Financial performance
8.4.13.3. Product benchmarking
8.4.13.4. Strategic initiatives
8.4.14. eClinicalWorks LLC
8.4.14.1. Company overview
8.4.14.2. Financial performance
8.4.14.3. Product benchmarking
8.4.14.4. Strategic initiatives