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 Phosphoramidite Market Size, Share & Trends Analysis Report By Type (DNA Phosphoramidites, RNA Phosphoramidites), By Application (Drug Discovery & Development, Diagnostics Development), By End Use, By Region, And Segment Forecasts, 2025 - 2033
Phosphoramidite Market Summary The global phosphoramidite market size was estimated at USD 1.15 billion in 2024 and is projected to reach USD 2.27 billion by 2033, growing at a CAGR of 8.06% fr... もっと見る
SummaryPhosphoramidite Market SummaryThe global phosphoramidite market size was estimated at USD 1.15 billion in 2024 and is projected to reach USD 2.27 billion by 2033, growing at a CAGR of 8.06% from 2025 to 2033. The market growth can be attributed to the increasing demand for phosphoramidite in the production of oligonucleotides, the rising prevalence of genetic disorders and infectious diseases has led to a surge in research and development activities in the biotechnology and pharmaceutical industries, which further fuels the demand for phosphoramidite. Moreover, the growing geriatric population and increasing healthcare expenditure are also expected to drive the market growth in the coming years. Rising Demand for Oligonucleotide Therapeutics The increasing adoption of oligonucleotide-based therapeutics is a major growth driver for the phosphoramidite industry. Pharmaceutical and biotechnology companies are investing heavily in the development of antisense oligonucleotides (ASOs), small interfering RNAs (siRNA), and messenger RNA (mRNA) therapies to address a wide range of genetic, infectious, and rare diseases. These therapies rely on precisely synthesized oligonucleotides, with phosphoramidites serving as the essential chemical intermediates for constructing nucleotide chains. The success of mRNA vaccines during the COVID-19 pandemic has further validated the therapeutic potential of synthetic RNA, accelerating research and regulatory acceptance of oligo-based modalities. ASOs and siRNAs are gaining prominence as next-generation therapeutics due to their ability to selectively silence or modulate gene expression. Multiple ASO-based drugs have already received regulatory approvals, and a robust pipeline is in development targeting neurological disorders, cancers, and metabolic conditions. As the therapeutic landscape shifts towards nucleic acid-based solutions, the demand for high-purity, modified, and scalable phosphoramidites is growing exponentially. Drug developers require consistent and high-quality oligonucleotides that meet stringent regulatory standards for safety and efficacy, thereby increasing reliance on trusted suppliers with proven synthesis capabilities. In addition, mRNA therapeutics are being explored beyond vaccines, including applications in oncology, cardiovascular diseases, and protein replacement therapies. These advancements demand more complex and specialized phosphoramidites for coding sequences, modified caps, and regulatory elements. This trend is prompting strategic partnerships between oligo manufacturers and pharmaceutical innovators to ensure secure supply chains, technological integration, and quality assurance. With the global pipeline for nucleic acid drugs expanding and clinical trials accelerating, the phosphoramidite industry is well-positioned for long-term growth as a foundational enabler of oligonucleotide therapeutics. Global Phosphoramidite Market Report Segmentation This report forecasts revenue growth and provides an analysis of the latest trends in each of the sub-segments from 2021 to 2033. For this report, Grand View Research has segmented the global phosphoramidite market based on type, application, end use, and region. • Type Outlook (Revenue, USD Million, 2021 - 2033) • DNA Phosphoramidites • RNA Phosphoramidites • Labeled Phosphoramidites • Modifier Phosphoramidites • Others • Application Outlook (Revenue, USD Million, 2021 - 2033) • Drug Discovery & Development • Diagnostics Development • Others • End Use Outlook (Revenue, USD Million, 2021 - 2033) • Pharmaceutical & Biotechnology Companies • Academic & Research Institutes • Others • Regional Outlook (Revenue, USD Million, 2021 - 2033) • North America o U.S. o Canada o Mexico • Europe o UK o Germany o France o Italy o Spain o Denmark o Sweden o Norway • Asia Pacific o Japan o China o India o Australia o Thailand o South Korea • Latin America o Brazil o Argentina • Middle East and Africa (MEA) o South Africa o Saudi Arabia o UAE o Kuwait Table of ContentsTable of ContentsChapter 1. Methodology and Scope 1.1. Market Segmentation and Scope 1.2. Market Definitions 1.2.1. Type 1.2.2. Application 1.2.3. End Use 1.3. Information analysis 1.4. Market formulation & data visualization 1.5. Data validation & publishing 1.6. Information Procurement 1.6.1. Primary Research 1.7. Information or Data Analysis 1.8. Market Formulation & Validation 1.9. Market Model 1.10. Objectives Chapter 2. Executive Summary 2.1. Market Outlook 2.2. Segment Snapshot 2.3. Competitive Landscape Snapshot Chapter 3. Market Variables, Trends, & Scope 3.1. Market Lineage Outlook 3.1.1. Parent Market Outlook 3.1.2. Related/Ancillary Market Outlook 3.2. Market Dynamics 3.2.1. Market Driver Analysis 3.2.1.1. Growth of oligonucleotide therapies 3.2.1.2. Advancements in genomics and personalized medicine 3.2.1.3. Growth in synthetic biology research 3.2.2. Market Restraint Analysis 3.2.2.1. Stringent regulations for oligonucleotide therapies 3.2.2.2. Difficulties in long chain synthesis 3.3. Industry Analysis Tools 3.3.1. Porter's Five Forces Analysis 3.3.2. PESTEL Analysis Chapter 4. Phosphoramidite Market: Type Business Analysis 4.1. Type Segment Dashboard 4.2. Global Phosphoramidite Market Type Movement Analysis 4.3. Global Phosphoramidite Market Size & Trend Analysis, by Type, 2021 to 2033 (USD Million) 4.4. DNA Phosphoramidites 4.4.1. Global DNA Phosphoramidites Market Estimates and Forecasts, 2021 - 2033 (USD Million) 4.5. RNA Phosphoramidites 4.5.1. Global RNA Phosphoramidites Market Estimates and Forecasts, 2021 - 2033 (USD Million) 4.6. Labeled Phosphoramidites 4.6.1. Global Labeled Phosphoramidites Market Estimates and Forecasts, 2021 - 2033 (USD Million) 4.7. Modifier Phosphoramidites 4.7.1. Global Modifier Phosphoramidites Market Estimates and Forecasts, 2021 - 2033 (USD Million) 4.8. Others 4.8.1. Global Others Market Estimates and Forecasts, 2021 - 2033 (USD Million) Chapter 5. Phosphoramidite Market: Application Business Analysis 5.1. Application Segment Dashboard 5.2. Global Phosphoramidite Market Application, Movement Analysis 5.3. Global Phosphoramidite Market Size & Trend Analysis, by Application, 2021 to 2033 (USD Million) 5.4. Drug Discovery & Development 5.4.1. Global Drug Discovery & DevelopmentMarket Estimates and Forecasts, 2021 - 2033 (USD Million) 5.5. Diagnostics Development 5.5.1. Global Diagnostics Development Market Estimates and Forecasts, 2021 - 2033 (USD Million) 5.6. Others 5.6.1. Global Others Market Estimates and Forecasts, 2021 - 2033 (USD Million) Chapter 6. Phosphoramidite Market: End Use Business Analysis 6.1. End Use Segment Dashboard 6.2. Global Phosphoramidite Market End Use Movement Analysis 6.3. Global Phosphoramidite Market Size & Trend Analysis, by End Use, 2021 to 2033 (USD Million) 6.4. Pharmaceutical & Biotechnology Companies 6.4.1. Global Pharmaceutical & Biotechnology Companies Market Estimates and Forecasts, 2021 - 2033 (USD Million) 6.5. Academic & Research Institutes 6.5.1. Global Academic & Research Institutes Market Estimates and Forecasts, 2021 - 2033 (USD Million) 6.6. Others 6.6.1. Global Others Market Estimates and Forecasts, 2021 - 2033 (USD Million) Chapter 7. Phosphoramidite Market: Regional Estimates & Trend Analysis 7.1. Regional Dashboard 7.2. Market Size & Forecasts and Trend Analysis, 2018 to 2030 7.3. North America 7.3.1. North America Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.3.2. U.S. 7.3.2.1. Key Country Dynamics 7.3.2.2. Competitive Scenario 7.3.2.3. Regulatory Framework 7.3.2.4. U.S. Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.3.3. Canada 7.3.3.1. Key Country Dynamics 7.3.3.2. Competitive Scenario 7.3.3.3. Regulatory Framework 7.3.3.4. Canada Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.3.4. Mexico 7.3.4.1. Key Country Dynamics 7.3.4.2. Competitive Scenario 7.3.4.3. Regulatory Framework 7.3.4.4. Mexico Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.4. Europe 7.4.1. Europe Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.4.2. UK 7.4.2.1. Key Country Dynamics 7.4.2.2. Competitive Scenario 7.4.2.3. Regulatory Framework 7.4.2.4. UK Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.4.3. Germany 7.4.3.1. Key Country Dynamics 7.4.3.2. Competitive Scenario 7.4.3.3. Regulatory Framework 7.4.3.4. Germany Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.4.4. France 7.4.4.1. Key Country Dynamics 7.4.4.2. Competitive Scenario 7.4.4.3. Regulatory Framework 7.4.4.4. France Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.4.5. Italy 7.4.5.1. Key Country Dynamics 7.4.5.2. Competitive Scenario 7.4.5.3. Regulatory Framework 7.4.5.4. Italy Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.4.6. Spain 7.4.6.1. Key Country Dynamics 7.4.6.2. Competitive Scenario 7.4.6.3. Regulatory Framework 7.4.6.4. Spain Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.4.7. Denmark 7.4.7.1. Key Country Dynamics 7.4.7.2. Competitive Scenario 7.4.7.3. Regulatory Framework 7.4.7.4. Denmark Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.4.8. Sweden 7.4.8.1. Key Country Dynamics 7.4.8.2. Competitive Scenario 7.4.8.3. Regulatory Framework 7.4.8.4. Sweden Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.4.9. Norway 7.4.9.1. Key Country Dynamics 7.4.9.2. Competitive Scenario 7.4.9.3. Regulatory Framework 7.4.9.4. Norway Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.5. Asia Pacific 7.5.1. Asia Pacific Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.5.2. Japan 7.5.2.1. Key Country Dynamics 7.5.2.2. Competitive Scenario 7.5.2.3. Regulatory Framework 7.5.2.4. Japan Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.5.3. China 7.5.3.1. Key Country Dynamics 7.5.3.2. Competitive Scenario 7.5.3.3. Regulatory Framework 7.5.3.4. China Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.5.4. India 7.5.4.1. Key Country Dynamics 7.5.4.2. Competitive Scenario 7.5.4.3. Regulatory Framework 7.5.4.4. India Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.5.5. Australia 7.5.5.1. Key Country Dynamics 7.5.5.2. Competitive Scenario 7.5.5.3. Regulatory Framework 7.5.5.4. Australia Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.5.6. Thailand 7.5.6.1. Key Country Dynamics 7.5.6.2. Competitive Scenario 7.5.6.3. Regulatory Framework 7.5.6.4. Thailand Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.5.7. South Korea 7.5.7.1. Key Country Dynamics 7.5.7.2. Competitive Scenario 7.5.7.3. Regulatory Framework 7.5.7.4. South Korea Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.6. Latin America 7.6.1. Latin America Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.6.2. Brazil 7.6.2.1. Key Country Dynamics 7.6.2.2. Competitive Scenario 7.6.2.3. Regulatory Framework 7.6.2.4. Brazil Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.6.3. Argentina 7.6.3.1. Key Country Dynamics 7.6.3.2. Competitive Scenario 7.6.3.3. Regulatory Framework 7.6.3.4. Argentina Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.7. MEA 7.7.1. MEA Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.7.2. South Africa 7.7.2.1. Key Country Dynamics 7.7.2.2. Competitive Scenario 7.7.2.3. Regulatory Framework 7.7.2.4. South Africa Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.7.3. Saudi Arabia 7.7.3.1. Key Country Dynamics 7.7.3.2. Competitive Scenario 7.7.3.3. Regulatory Framework 7.7.3.4. Saudi Arabia Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.7.4. UAE 7.7.4.1. Key Country Dynamics 7.7.4.2. Competitive Scenario 7.7.4.3. Regulatory Framework 7.7.4.4. UAE Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) 7.7.5. Kuwait 7.7.5.1. Key Country Dynamics 7.7.5.2. Competitive Scenario 7.7.5.3. Regulatory Framework 7.7.5.4. Kuwait Phosphoramidite Market Estimates and Forecasts, 2021 - 2033 (USD Million) Chapter 8. Competitive Landscape 8.1. Participant Categorization 8.2. Strategy Mapping 8.3. Company Market Position Analysis, 2024 8.4. Participant’s Overview 8.4.1. BOC Sciences 8.4.1.1. Overview 8.4.1.2. Financial Performance 8.4.1.3. Product Benchmarking 8.4.1.4. Strategic Initiatives 8.4.2. Thermo Fisher Scientific Inc. 8.4.2.1. Overview 8.4.2.2. Financial Performance 8.4.2.3. Product Benchmarking 8.4.2.4. Strategic Initiatives 8.4.3. Merck KGaA 8.4.3.1. Overview 8.4.3.2. Financial Performance 8.4.3.3. Product Benchmarking 8.4.3.4. Strategic Initiatives 8.4.4. Glen Research 8.4.4.1. Overview 8.4.4.2. Financial Performance 8.4.4.3. Product Benchmarking 8.4.4.4. Strategic Initiatives 8.4.5. LGC Biosearch Technologies 8.4.5.1. Overview 8.4.5.2. Financial Performance 8.4.5.3. Product Benchmarking 8.4.5.4. Strategic Initiatives 8.4.6. Biosynth 8.4.6.1. Overview 8.4.6.2. Financial Performance 8.4.6.3. Product Benchmarking 8.4.6.4. Strategic Initiatives 8.4.7. BIONEER CORPORATION 8.4.7.1. Overview 8.4.7.2. Financial Performance 8.4.7.3. Product Benchmarking 8.4.7.4. Strategic Initiatives 8.4.8. QIAGEN 8.4.8.1. Overview 8.4.8.2. Financial Performance 8.4.8.3. Product Benchmarking 8.4.8.4. Strategic Initiatives 8.4.9. PolyOrg, Inc 8.4.9.1. Overview 8.4.9.2. Financial Performance 8.4.9.3. Product Benchmarking 8.4.9.4. Strategic Initiatives 8.4.10. Lumiprobe Corporation 8.4.10.1. Overview 8.4.10.2. Financial Performance 8.4.10.3. Product Benchmarking 8.4.10.4. Strategic Initiatives
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