Summary

Market Size & Trends
The U.S. protein purification and isolation market size was valued at USD 3.41 billion in 2024 and is projected to reach USD 8.06 billion by 2033, growing at a CAGR of 10.09% from 2025 to 2033, driven by increasing demand for biopharmaceuticals, advancements in protein-based research, and the rising need for high-purity biologics in clinical and diagnostic applications.


U.S. Protein Purification And Isolation Market Report Segmentation

This report forecasts revenue growth and provides an analysis on the latest trends in each of the sub-segments from 2021 to 2033. For the purpose of this report, Grand View Research has segmented the U.S. protein purification and isolation market on the basis of product, technology, application, and end use.

• Product Outlook (Revenue, USD Million, 2021 - 2033)
• Instruments
• Consumables
o Kits
o Reagents
o Columns
o Magnetic Beads
o Resins
o Others
• Technology Outlook (Revenue, USD Million, 2021 - 2033)
• Ultrafiltration
• Precipitation
• Chromatography
o Ion Exchange Chromatography
o Affinity Chromatography
o Reversed Phase Chromatography
o Size Exclusion Chromatography
o Hydrophobic Interaction Chromatography
• Electrophoresis
o Gel Electrophoresis
o Isoelectric Focusing
o Capillary Electrophoresis
• Western Blotting
• Others
• Application Outlook (Revenue, USD Million, 2021 - 2033)
• Drug Screening
• Biomarker Discovery
• Protein-Protein Interaction Studies
• Diagnostics
• End Use Outlook (Revenue, USD Million, 2021 - 2033)
• Academic And Research Institutes
• Hospitals
• Pharmaceutical And Biotechnology Companies
• CROs

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Table of Contents

Table of Contents

Chapter 1. Methodology and Scope
1.1. Market Segmentation & Scope
1.2. Market Definitions
1.2.1. Product Segment
1.2.2. Technology Segment
1.2.3. Application Segment
1.2.4. End Use Segment
1.3. Information analysis
1.3.1. Market formulation & data visualization
1.4. Data validation & publishing
1.5. Information Procurement
1.5.1. Primary Research
1.6. Information or Data Analysis
1.7. Market Formulation & Validation
1.8. Market Model
1.9. Total Market: CAGR Calculation
1.10. Objectives
Chapter 2. Executive Summary
2.1. Market Outlook
2.2. Segmental Snapshot
2.3. Competitive Landscape Snapshot
Chapter 3. Market Variables, Trends, and Scope
3.1. Market Lineage
3.1.1. Parent Market Analysis
3.1.2. Ancillary Market Analysis
3.2. Protein Purification and Isolation Market - Market Dynamics
3.2.1. Market Driver Analysis
3.2.1.1. Increased research in proteomics and genomics
3.2.1.2. Rising demand from the diagnostic sector
3.2.2. Market Restraint Analysis
3.2.2.1. High cost of advanced purification technologies
3.2.2.2. Technical complexity and skill dependency
3.3. Market Analysis Tools
3.3.1. Porter’s Five Forces Analysis
3.3.2. PESTLE Analysis
Chapter 4. U.S. Protein Purification and Isolation Market: Product Business Analysis
4.1. Product Segment Dashboard
4.2. U.S. Protein Purification and Isolation Market Product Movement Analysis, 2024 & 2033
4.3. U.S. Protein Purification and Isolation Market Size & Trend Analysis, by Product, 2021 to 2033 (USD Million)
4.4. Instrument
4.4.1. U.S. Instrument Market Estimates and Forecasts, 2021 - 2033 (USD Million)
4.5. Consumables
4.5.1. U.S. Consumables Market Revenue Estimates and Forecasts, 2021 - 2033 (USD Million)
4.5.2. Kits
4.5.2.1. U.S. Kits Market Estimates and Forecasts, 2021 - 2033 (USD Million)
4.5.3. Reagents
4.5.3.1. U.S. Reagents Market Estimates and Forecasts, 2021 - 2033 (USD Million)
4.5.4. Columns
4.5.4.1. U.S. Columns Market Estimates and Forecasts, 2021 - 2033 (USD Million)
4.5.5. Magnetic Beads
4.5.5.1. U.S. Magnetic Beads Market Estimates and Forecasts, 2021 - 2033 (USD Million)
4.5.6. Resins
4.5.6.1. U.S. Resins Market Estimates and Forecasts, 2021 - 2033 (USD Million)
4.5.7. Others
4.5.7.1. U.S. Others Market Estimates and Forecasts, 2021 - 2033 (USD Million)
Chapter 5. U.S. Protein Purification and Isolation Market: Technology Business Analysis
5.1. Technology Segment Dashboard
5.2. U.S. Protein Purification and Isolation Market Technology Movement Analysis, 2024 & 2033
5.3. U.S. Protein Purification and Isolation Market Size & Trend Analysis, by Technology, 2021 to 2033 (USD Million)
5.4. Ultrafiltration
5.4.1. U.S. Ultrafiltration Market Estimates And Forecasts, 2021 - 2033 (USD Million)
5.5. Precipitation
5.5.1. U.S. Precipitation Market Estimates And Forecasts, 2021 - 2033 (USD Million)
5.6. Chromatography
5.6.1. U.S. Chromatography Market Estimates And Forecasts, 2021 - 2033 (USD Million)
5.6.2. Ion Exchange Chromatography
5.6.2.1. U.S. Ion Exchange Chromatography Market Estimates And Forecasts, 2021 - 2033 (USD Million)
5.6.3. Affinity Chromatography
5.6.3.1. U.S. Affinity Chromatography Market Estimates And Forecasts, 2021 - 2033 (USD Million)
5.6.4. Reversed Phase Chromatography
5.6.4.1. U.S. Reversed Phase Chromatography Market Estimates And Forecasts, 2021 - 2033 (USD Million)
5.6.5. Size Exclusion Chromatography
5.6.5.1. U.S. Size Exclusion Chromatography Market Estimates And Forecasts, 2021 - 2033 (USD Million)
5.6.6. Hydrophobic Interaction Chromatography
5.6.6.1. U.S. Hydrophobic Interaction Chromatography Market Estimates And Forecasts, 2021 - 2033 (USD Million)
5.7. Electrophoresis
5.7.1. U.S. Electrophoresis Market Estimates And Forecasts, 2021 - 2033 (USD Million)
5.7.2. Gel Electrophoresis
5.7.2.1. U.S. Gel Electrophoresis Market Estimates And Forecasts, 2021 - 2033 (USD Million)
5.7.3. Isoelectric Focusing
5.7.3.1. U.S. Isoelectric Focusing Market Estimates And Forecasts, 2021 - 2033 (USD Million)
5.7.4. Capillary Electrophoresis
5.7.4.1. U.S. Capillary Electrophoresis Market Estimates And Forecasts, 2021 - 2033 (USD Million)
5.8. Western Blotting
5.8.1. U.S. Western Blotting Market Estimates And Forecasts, 2021 - 2033 (USD Million)
5.9. Others
5.9.1. U.S. Others Market Estimates And Forecasts, 2021 - 2033 (USD Million)
Chapter 6. U.S. Protein Purification and Isolation Market: Application Business Analysis
6.1. Application Segment Dashboard
6.2. U.S. Protein Purification and Isolation Market Application Movement Analysis, 2024 & 2033
6.3. U.S. Protein Purification and Isolation Market Size & Trend Analysis, by Application, 2021 to 2033 (USD Million)
6.4. Biomarker Discovery
6.4.1. U.S. Biomarker Discovery Market Estimates And Forecasts, 2021 - 2033 (USD Million)
6.5. Drug Screening
6.5.1. U.S. Drug Screening Market Estimates And Forecasts, 2021 - 2033 (USD Million)
6.6. Diagnostics
6.6.1. U.S. Diagnostics Market Estimates And Forecasts, 2021 - 2033 (USD Million)
6.7. Protein-Protein Interaction Studies
6.7.1. U.S. Protein-Protein Interaction Studies Market Estimates And Forecasts, 2021 - 2033 (USD Million)
Chapter 7. U.S. Protein Purification and Isolation Market: End Use Business Analysis
7.1. End Use Segment Dashboard
7.2. U.S. Protein Purification and Isolation Market End Use Movement Analysis, 2024 & 2033
7.3. U.S. Protein Purification and Isolation Market Size & Trend Analysis, by End Use, 2021 to 2033 (USD Million)
7.4. Pharmaceutical & Biotechnology Companies
7.4.1. U.S. Pharmaceutical & Biotechnology Companies Market Estimates And Forecasts, 2021 - 2033 (USD Million)
7.5. Hospitals
7.5.1. U.S. Hospitals Market Estimates And Forecasts, 2021 - 2033 (USD Million)
7.6. Academic and Research Institutions
7.6.1. U.S. Academic and Research Institutions Market Estimates And Forecasts, 2021 - 2033 (USD Million)
7.7. CROs
7.7.1. U.S. CROs Market Estimates And Forecasts, 2021 - 2033 (USD Million)
Chapter 8. Competitive Landscape
8.1. Company/Competition Categorization
8.2. Strategy Mapping
8.3. Company Market Position Analysis, 2024
8.4. Company Profiles/Listing
8.4.1. Thermo Fisher Scientific Inc.
8.4.1.1. Company overview
8.4.1.2. Financial performance
8.4.1.3. Technology benchmarking
8.4.1.4. Strategic initiatives
8.4.2. Merck KGaA
8.4.2.1. Company overview
8.4.2.2. Financial performance
8.4.2.3. Technology benchmarking
8.4.2.4. Strategic initiatives
8.4.3. QIAGEN
8.4.3.1. Company overview
8.4.3.2. Financial performance
8.4.3.3. Technology benchmarking
8.4.3.4. Strategic initiatives
8.4.4. Bio-Rad Laboratories, Inc.
8.4.4.1. Company overview
8.4.4.2. Financial performance
8.4.4.3. Technology benchmarking
8.4.4.4. Strategic initiatives
8.4.5. Agilent Technologies, Inc.
8.4.5.1. Company overview
8.4.5.2. Financial performance
8.4.5.3. Technology benchmarking
8.4.5.4. Strategic initiatives
8.4.6. Cube Biotech GmbH
8.4.6.1. Company overview
8.4.6.2. Financial performance
8.4.6.3. Technology benchmarking
8.4.6.4. Strategic initiatives
8.4.7. Promega Corporation
8.4.7.1. Company overview
8.4.7.2. Financial performance
8.4.7.3. Technology benchmarking
8.4.7.4. Strategic initiatives
8.4.8. Norgen Biotek Corp.
8.4.8.1. Company overview
8.4.8.2. Financial performance
8.4.8.3. Technology benchmarking
8.4.8.4. Strategic initiatives
8.4.9. Takara Bio. Inc.
8.4.9.1. Company overview
8.4.9.2. Financial performance
8.4.9.3. Technology benchmarking
8.4.9.4. Strategic initiatives
8.4.10. Danaher
8.4.10.1. Company overview
8.4.10.2. Financial performance
8.4.10.3. Technology benchmarking
8.4.10.4. Strategic initiatives