Summary

Market Overview

According to DIResearch＇s in-depth investigation and research, the global Silk Fibroin (SF) market size will reach 130.91 Million USD in 2026 and is projected to reach 198.67 Million USD by 2033, with a CAGR of 6.14% (2026-2033). Notably, the China Silk Fibroin (SF) market has changed rapidly in the past few years. By 2026, China＇s market size is expected to be Million USD, representing approximately % of the global market share.

Research Summary

Silk fibroin (SF) is a natural fibrous protein primarily derived from silkworm cocoons, accounting for 70–80% of the total silk weight. Composed mainly of amino acids such as glycine, alanine, and serine, it features a unique combination of β-sheet structures and random coil regions, which confer high strength, excellent toughness, and flexible processability. In addition to its outstanding mechanical properties, silk fibroin exhibits good biocompatibility and biodegradability, gradually breaking down into amino acids in the body. It is widely used in tissue engineering scaffolds, biodegradable sutures, drug delivery systems, as well as high-end textiles and functional materials. Its natural renewability, versatile processing potential, and compatibility with the human body make it highly valuable in biomedical and material science applications.

The major global  manufacturers of Silk Fibroin (SF) include Worldway Co., Ltd, Croda International, AMSilk GmbH, Zhejiang Cathaya International Co., Ltd, Zhejiang Xingyue Biotechnology Co.,Ltd, Suzhou Soho Biomaterials Technology Co.,Ltd, Nanjing Siyuan Medical Technology Co., Ltd., Favorsun, Kelisema Srl, CellaMatrix, Cocoon Biotech, Sollice Biotech, Caresilk, Strong Biologics, Shanghai Siyan Biotechnology Co., Ltd, Fibroheal Woundcare, Bugamed Biotechnology Inc, Nagasuna mayu inc, etc. The global players competition landscape in this report is divided into three tiers. The first tier comprises global leading enterprises that command a substantial market share, hold a dominant industry position, possess strong competitiveness and influence, and generate significant revenue. The second tier includes companies with a notable market presence and reputation; these firms actively follow industry leaders in product, service, or technological innovation and maintain a moderate revenue scale. The third tier consists of smaller companies with limited market share and lower brand recognition, primarily focused on local markets and generating comparatively lower revenue.

This report studies the market size, price trends and future development prospects of Silk Fibroin (SF). Focus on analysing the market share, product portfolio, prices, sales, revenue and gross profit margin of global major manufacturers, as well as the market status and trends of different product types and applications in the global Silk Fibroin (SF) market. The report data covers historical data from 2021 to 2025, based year in 2026 and forecast data from 2027 to 2033.

The regions and countries in the report include North America, Europe, China, APAC (excl. China), Latin America and Middle East and Africa, covering the Silk Fibroin (SF) market conditions and future development trends of key regions and countries, combined with industry-related policies and the latest technological developments, analyze the development characteristics of Silk Fibroin (SF) industries in various regions and countries, help companies understand the development characteristics of each region, help companies formulate business strategies, and achieve the ultimate goal of the company's global development strategy.  

The data sources of this report mainly include the National Bureau of Statistics, customs databases, industry associations, corporate financial reports, third-party databases, etc. Among them, macroeconomic data mainly comes from the National Bureau of Statistics, International Economic Research Organization; industry statistical data mainly come from industry associations; company data mainly comes from interviews, public information collection, third-party reliable databases, and price data mainly comes from various markets monitoring database.

Global Key Manufacturers of Silk Fibroin (SF) Include:

Worldway Co., Ltd

Croda International

AMSilk GmbH

Zhejiang Cathaya International Co., Ltd

Zhejiang Xingyue Biotechnology Co.,Ltd

Suzhou Soho Biomaterials Technology Co.,Ltd

Nanjing Siyuan Medical Technology Co., Ltd.

Favorsun

Kelisema Srl

CellaMatrix

Cocoon Biotech

Sollice Biotech

Caresilk

Strong Biologics

Shanghai Siyan Biotechnology Co., Ltd

Fibroheal Woundcare

Bugamed Biotechnology Inc

Nagasuna mayu inc

Silk Fibroin (SF) Product Segment Include:

Silk Fibroin (30–300 kDa)

Silk Peptides (500–30,000 Da)

Silk Amino Acids (75–500 Da)

Silk Fibroin (SF) Product Application Include:

Personal Care

Biomedicine

Others




Chapter Scope

Chapter 1: Product Research Range, Product Types and Applications, Market Overview, Market Situation and Trends

Chapter 2: Global Silk Fibroin (SF) Industry PESTEL Analysis

Chapter 3: Global Silk Fibroin (SF) Industry Porter’s Five Forces Analysis

Chapter 4: Global Silk Fibroin (SF) Major Regional Market Size (Revenue, Sales, Price) and Forecast Analysis

Chapter 5: Global Silk Fibroin (SF) Market Size and Forecast by Type and Application Analysis

Chapter 6: North America Silk Fibroin (SF) Competitive Analysis (Market Size, Key Players and Market Share, Product Type and Application Segment Analysis, Countries Analysis)

Chapter 7: Europe Silk Fibroin (SF) Competitive Analysis (Market Size, Key Players and Market Share, Product Type and Application Segment Analysis, Countries Analysis)

Chapter 8: China Silk Fibroin (SF) Competitive Analysis (Market Size, Key Players and Market Share, Product Type and Application Segment Analysis, Countries Analysis)

Chapter 9: APAC (Excl. China) Silk Fibroin (SF) Competitive Analysis (Market Size, Key Players and Market Share, Product Type and Application Segment Analysis, Countries Analysis)

Chapter 10: Latin America Silk Fibroin (SF) Competitive Analysis (Market Size, Key Players and Market Share, Product Type and Application Segment Analysis, Countries Analysis)

Chapter 11: Middle East and Africa Silk Fibroin (SF) Competitive Analysis (Market Size, Key Players and Market Share, Product Type and Application Segment Analysis, Countries Analysis)

Chapter 12: Global Silk Fibroin (SF) Competitive Analysis of Key Manufacturers (Sales, Revenue, Market Share, Price, Regional Distribution and Industry Concentration)

Chapter 13: Key Company Profiles (Product Portfolio, Sales, Revenue, Price and Gross Margin)

Chapter 14: Industrial Chain Analysis, Include Raw Material Suppliers, Distributors and Customers

Chapter 15: Research Findings and Conclusion

Chapter 16: Methodology and Data Sources

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Table of Contents

Table of Contents

1 Silk Fibroin (SF) Market Overview

  1.1 Product Definition and Statistical Scope

   1.2 Silk Fibroin (SF) Product by Type

       1.2.1 Silk Fibroin (30–300 kDa)

       1.2.2 Silk Peptides (500–30,000 Da)

       1.2.3 Silk Amino Acids (75–500 Da)

   1.3 Silk Fibroin (SF) Product by Application

       1.3.1 Personal Care

       1.3.2 Biomedicine

       1.3.3 Others

  1.4 Global Silk Fibroin (SF) Market Revenue and Sales Analysis

       1.4.1 Global Silk Fibroin (SF) Revenue Market Size Analysis (2021-2033)

       1.4.2 Global Silk Fibroin (SF) Sales Market Size Analysis (2021-2033)

       1.4.3 Global Silk Fibroin (SF) Market Sales Price Trend Analysis (2021-2033)

  1.5 Silk Fibroin (SF) Industry Trends and Innovation

       1.5.1 Silk Fibroin (SF) Industry Trends and Innovation

       1.5.2 Silk Fibroin (SF) Market Drivers and Challenges

2 Silk Fibroin (SF) Market PESTEL Analysis

   2.1 Political Factors Analysis

   2.2 Economic Factors Analysis

   2.3 Social Factors Analysis

   2.4 Technological Factors Analysis

   2.5 Environmental Factors Analysis

   2.6 Legal Factors Analysis

3 Silk Fibroin (SF) Market Porter's Five Forces Analysis

   3.1 Competitive Rivalry

   3.2 Threat of New Entrants

   3.3 Bargaining Power of Suppliers

   3.4 Bargaining Power of Buyers

   3.5 Threat of Substitutes

4 Global Silk Fibroin (SF) Market Analysis by Regions

   4.1 Silk Fibroin (SF) Overall Market: 2025 VS 2026 VS 2033

   4.2 Global Silk Fibroin (SF) Revenue and Forecast Analysis (2021-2033)

       4.2.1 Global Silk Fibroin (SF) Revenue and Market Share by Region (2021-2026)

       4.2.2 Global Silk Fibroin (SF) Revenue and Market Share Forecast by Region (2027-2033)

   4.3 Global Silk Fibroin (SF) Sales and Forecast Analysis (2021-2033)

       4.3.1 Global Silk Fibroin (SF) Sales and Market Share by Region (2021-2026)

       4.3.2 Global Silk Fibroin (SF) Sales and Market Share Forecast by Region (2027-2033)

   4.4 Global Silk Fibroin (SF) Sales Price Trend Analysis (2021-2033)

5 Global Silk Fibroin (SF) Market Size by Type and Application

   5.1 Global Silk Fibroin (SF) Market Size by Type

       5.1.1 Global Silk Fibroin (SF) Revenue and Forecast Analysis by Type (2021-2033)

       5.1.2 Global Silk Fibroin (SF) Sales and Forecast Analysis by Type (2021-2033)

   5.2 Global Silk Fibroin (SF) Market Size by Application

       5.2.1 Global Silk Fibroin (SF) Revenue and Forecast Analysis by Application (2021-2033)

       5.2.2 Global Silk Fibroin (SF) Sales and Forecast Analysis by Application (2021-2033)

6 North America

   6.1 North America Silk Fibroin (SF) Market Size and Growth Rate Analysis (2021-2033)

   6.2 North America Key Manufacturers Analysis

   6.3 North America Silk Fibroin (SF) Market Size by Type

       6.3.1 North America Silk Fibroin (SF) Sales by Type (2021-2033)

       6.3.2 North America Silk Fibroin (SF) Revenue by Type (2021-2033)

   6.4 North America Silk Fibroin (SF) Market Size by Application

       6.4.1 North America Silk Fibroin (SF) Sales by Application (2021-2033)

       6.4.2 North America Silk Fibroin (SF) Revenue by Application (2021-2033)

   6.5 North America Silk Fibroin (SF) Market Size by Country

       6.5.1 US

       6.5.2 Canada

7 Europe

   7.1 Europe Silk Fibroin (SF) Market Size and Growth Rate Analysis (2021-2033)

   7.2 Europe Key Manufacturers Analysis

   7.3 Europe Silk Fibroin (SF) Market Size by Type

       7.3.1 Europe Silk Fibroin (SF) Sales by Type (2021-2033)

       7.3.2 Europe Silk Fibroin (SF) Revenue by Type (2021-2033)

   7.4 Europe Silk Fibroin (SF) Market Size by Application

       7.4.1 Europe Silk Fibroin (SF) Sales by Application (2021-2033)

       7.4.2 Europe Silk Fibroin (SF) Revenue by Application (2021-2033)

   7.5 Europe Silk Fibroin (SF) Market Size by Country

       7.5.1 Germany

       7.5.2 France

       7.5.3 United Kingdom

       7.5.4 Italy

       7.5.5 Spain

       7.5.6 Benelux

8 China

   8.1 China Silk Fibroin (SF) Market Size and Growth Rate Analysis (2021-2033)

   8.2 China Key Manufacturers Analysis

   8.3 China Silk Fibroin (SF) Market Size by Type

       8.3.1 China Silk Fibroin (SF) Sales by Type (2021-2033)

       8.3.2 China Silk Fibroin (SF) Revenue by Type (2021-2033)

   8.4 China Silk Fibroin (SF) Market Size by Application

       8.4.1 China Silk Fibroin (SF) Sales by Application (2021-2033)

       8.4.2 China Silk Fibroin (SF) Revenue by Application (2021-2033)

9 APAC (excl. China)

   9.1 APAC (excl. China) Silk Fibroin (SF) Market Size and Growth Rate Analysis (2021-2033)

   9.2 APAC (excl. China) Key Manufacturers Analysis

   9.3 APAC (excl. China) Silk Fibroin (SF) Market Size by Type

       9.3.1 APAC (excl. China) Silk Fibroin (SF) Sales by Type (2021-2033)

       9.3.2 APAC (excl. China) Silk Fibroin (SF) Revenue by Type (2021-2033)

   9.4 APAC (excl. China) Silk Fibroin (SF) Market Size by Application

       9.4.1 APAC (excl. China) Silk Fibroin (SF) Sales by Application (2021-2033)

       9.4.2 APAC (excl. China) Silk Fibroin (SF) Revenue by Application (2021-2033)

   9.5 APAC (excl. China) Silk Fibroin (SF) Market Size by Country

       9.5.1 Japan

       9.5.2 South Korea

       9.5.3 India

       9.5.4 Australia

       9.5.5 Southeast Asia

10 Latin America

   10.1 Latin America Silk Fibroin (SF) Market Size and Growth Rate Analysis (2021-2033)

   10.2 Latin America Key Manufacturers Analysis

   10.3 Latin America Silk Fibroin (SF) Market Size by Type

       10.3.1 Latin America Silk Fibroin (SF) Sales by Type (2021-2033)

       10.3.2 Latin America Silk Fibroin (SF) Revenue by Type (2021-2033)

   10.4 Latin America Silk Fibroin (SF) Market Size by Application

       10.4.1 Latin America Silk Fibroin (SF) Sales by Application (2021-2033)

       10.4.2 Latin America Silk Fibroin (SF) Revenue by Application (2021-2033)

   10.5 Latin America Silk Fibroin (SF) Market Size by Country

   10.6 Latin America Silk Fibroin (SF) Market Size by Country

       10.6.1 Mexico

       10.6.2 Brazil

11 Middle East & Africa

   11.1 Middle East & Africa Silk Fibroin (SF) Market Size and Growth Rate Analysis (2021-2033)

   11.2 Middle East & Africa Key Manufacturers Analysis

   11.3 Middle East & Africa Silk Fibroin (SF) Market Size by Type

       11.3.1 Middle East & Africa Silk Fibroin (SF) Sales by Type (2021-2033)

       11.3.2 Middle East & Africa Silk Fibroin (SF) Revenue by Type (2021-2033)

   11.4 Middle East & Africa Silk Fibroin (SF) Market Size by Application

       11.4.1 Middle East & Africa Silk Fibroin (SF) Sales by Application (2021-2033)

       11.4.2 Middle East & Africa Silk Fibroin (SF) Revenue by Application (2021-2033)

   11.5 Middle East Silk Fibroin (SF) Market Size by Country

       11.5.1 Saudi Arabia

       11.5.2 South Africa

12 Competition by Manufacturers

   12.1 Global Silk Fibroin (SF) Market Sales, Revenue and Price by Key Manufacturers (2021-2026)

       12.1.1 Global Silk Fibroin (SF) Market Sales by Key Manufacturers (2021-2026)

       12.1.2 Global Silk Fibroin (SF) Market Revenue by Key Manufacturers (2021-2026)

       12.1.3 Global Silk Fibroin (SF) Average Sales Price by Manufacturers (2021-2026)

   12.2 Silk Fibroin (SF) Competitive Landscape Analysis and Market Dynamic

       12.2.1 Silk Fibroin (SF) Competitive Landscape Analysis

       12.2.2 Global Key Manufacturers Headquarter Location and Key Area Sales

       12.2.3 Market Dynamic

13 Key Companies Analysis

   13.1 Worldway Co., Ltd

       13.1.1 Worldway Co., Ltd Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

       13.1.2 Worldway Co., Ltd Silk Fibroin (SF) Product Portfolio

       13.1.3 Worldway Co., Ltd Silk Fibroin (SF) Market Data Analysis (Revenue, Sales, Price, Gross Margin and Market Share) (2021-2026)

   13.2 Croda International

       13.2.1 Croda International Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

       13.2.2 Croda International Silk Fibroin (SF) Product Portfolio

       13.2.3 Croda International Silk Fibroin (SF) Market Data Analysis (Revenue, Sales, Price, Gross Margin and Market Share) (2021-2026)

   13.3 AMSilk GmbH

       13.3.1 AMSilk GmbH Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

       13.3.2 AMSilk GmbH Silk Fibroin (SF) Product Portfolio

       13.3.3 AMSilk GmbH Silk Fibroin (SF) Market Data Analysis (Revenue, Sales, Price, Gross Margin and Market Share) (2021-2026)

   13.4 Zhejiang Cathaya International Co., Ltd

       13.4.1 Zhejiang Cathaya International Co., Ltd Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

       13.4.2 Zhejiang Cathaya International Co., Ltd Silk Fibroin (SF) Product Portfolio

       13.4.3 Zhejiang Cathaya International Co., Ltd Silk Fibroin (SF) Market Data Analysis (Revenue, Sales, Price, Gross Margin and Market Share) (2021-2026)

   13.5 Zhejiang Xingyue Biotechnology Co.,Ltd

       13.5.1 Zhejiang Xingyue Biotechnology Co.,Ltd Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

       13.5.2 Zhejiang Xingyue Biotechnology Co.,Ltd Silk Fibroin (SF) Product Portfolio

       13.5.3 Zhejiang Xingyue Biotechnology Co.,Ltd Silk Fibroin (SF) Market Data Analysis (Revenue, Sales, Price, Gross Margin and Market Share) (2021-2026)

   13.6 Suzhou Soho Biomaterials Technology Co.,Ltd

       13.6.1 Suzhou Soho Biomaterials Technology Co.,Ltd Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

       13.6.2 Suzhou Soho Biomaterials Technology Co.,Ltd Silk Fibroin (SF) Product Portfolio

       13.6.3 Suzhou Soho Biomaterials Technology Co.,Ltd Silk Fibroin (SF) Market Data Analysis (Revenue, Sales, Price, Gross Margin and Market Share) (2021-2026)

   13.7 Nanjing Siyuan Medical Technology Co., Ltd.

       13.7.1 Nanjing Siyuan Medical Technology Co., Ltd. Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

       13.7.2 Nanjing Siyuan Medical Technology Co., Ltd. Silk Fibroin (SF) Product Portfolio

       13.7.3 Nanjing Siyuan Medical Technology Co., Ltd. Silk Fibroin (SF) Market Data Analysis (Revenue, Sales, Price, Gross Margin and Market Share) (2021-2026)

   13.8 Favorsun

       13.8.1 Favorsun Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

       13.8.2 Favorsun Silk Fibroin (SF) Product Portfolio

       13.8.3 Favorsun Silk Fibroin (SF) Market Data Analysis (Revenue, Sales, Price, Gross Margin and Market Share) (2021-2026)

   13.9 Kelisema Srl

       13.9.1 Kelisema Srl Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

       13.9.2 Kelisema Srl Silk Fibroin (SF) Product Portfolio

       13.9.3 Kelisema Srl Silk Fibroin (SF) Market Data Analysis (Revenue, Sales, Price, Gross Margin and Market Share) (2021-2026)

   13.10 CellaMatrix

       13.10.1 CellaMatrix Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

       13.10.2 CellaMatrix Silk Fibroin (SF) Product Portfolio

       13.10.3 CellaMatrix Silk Fibroin (SF) Market Data Analysis (Revenue, Sales, Price, Gross Margin and Market Share) (2021-2026)

   13.11 Cocoon Biotech

       13.11.1 Cocoon Biotech Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

       13.11.2 Cocoon Biotech Silk Fibroin (SF) Product Portfolio

       13.11.3 Cocoon Biotech Silk Fibroin (SF) Market Data Analysis (Revenue, Sales, Price, Gross Margin and Market Share) (2021-2026)

   13.12 Sollice Biotech

       13.12.1 Sollice Biotech Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

       13.12.2 Sollice Biotech Silk Fibroin (SF) Product Portfolio

       13.12.3 Sollice Biotech Silk Fibroin (SF) Market Data Analysis (Revenue, Sales, Price, Gross Margin and Market Share) (2021-2026)

   13.13 Caresilk

       13.13.1 Caresilk Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

       13.13.2 Caresilk Silk Fibroin (SF) Product Portfolio

       13.13.3 Caresilk Silk Fibroin (SF) Market Data Analysis (Revenue, Sales, Price, Gross Margin and Market Share) (2021-2026)

   13.14 Strong Biologics

       13.14.1 Strong Biologics Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

       13.14.2 Strong Biologics Silk Fibroin (SF) Product Portfolio

       13.14.3 Strong Biologics Silk Fibroin (SF) Market Data Analysis (Revenue, Sales, Price, Gross Margin and Market Share) (2021-2026)

   13.15 Shanghai Siyan Biotechnology Co., Ltd

       13.15.1 Shanghai Siyan Biotechnology Co., Ltd Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

       13.15.2 Shanghai Siyan Biotechnology Co., Ltd Silk Fibroin (SF) Product Portfolio

       13.15.3 Shanghai Siyan Biotechnology Co., Ltd Silk Fibroin (SF) Market Data Analysis (Revenue, Sales, Price, Gross Margin and Market Share) (2021-2026)

   13.16 Fibroheal Woundcare

       13.16.1 Fibroheal Woundcare Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

       13.16.2 Fibroheal Woundcare Silk Fibroin (SF) Product Portfolio

       13.16.3 Fibroheal Woundcare Silk Fibroin (SF) Market Data Analysis (Revenue, Sales, Price, Gross Margin and Market Share) (2021-2026)

   13.17 Bugamed Biotechnology Inc

       13.17.1 Bugamed Biotechnology Inc Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

       13.17.2 Bugamed Biotechnology Inc Silk Fibroin (SF) Product Portfolio

       13.17.3 Bugamed Biotechnology Inc Silk Fibroin (SF) Market Data Analysis (Revenue, Sales, Price, Gross Margin and Market Share) (2021-2026)

   13.18 Nagasuna mayu inc

       13.18.1 Nagasuna mayu inc Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

       13.18.2 Nagasuna mayu inc Silk Fibroin (SF) Product Portfolio

       13.18.3 Nagasuna mayu inc Silk Fibroin (SF) Market Data Analysis (Revenue, Sales, Price, Gross Margin and Market Share) (2021-2026)

14 Industry Chain Analysis

   14.1 Silk Fibroin (SF) Industry Chain Analysis

   14.2 Silk Fibroin (SF) Industry Raw Material and Suppliers Analysis

       14.2.1 Silk Fibroin (SF) Key Raw Material Supply Analysis

       14.2.2 Raw Material Suppliers and Contact Information

   14.3 Silk Fibroin (SF) Typical Downstream Customers

   14.4 Silk Fibroin (SF) Sales Channel Analysis

15 Research Findings and Conclusion

16 Methodology and Data Source

   16.1 Methodology/Research Approach

   16.2 Research Scope

   16.3 Benchmarks and Assumptions

   16.4 Date Source

       16.4.1 Primary Sources

       16.4.2 Secondary Sources

   16.5 Data Cross Validation

   16.6 Disclaimer