Summary

The Global NGS (Next-Generation Sequencing) Sample Preparation Market, valued at approximately USD 2.44 billion in 2024, is projected to expand at a remarkable CAGR of around 13.40% from 2025 to 2035. The NGS sample preparation process is a critical step in enabling high-throughput genomic analysis, ensuring that biological samples are transformed into high-quality sequencing-ready libraries. Over the past decade, the integration of NGS into clinical diagnostics, precision medicine, and advanced research has created a surging demand for faster, more reliable, and automation-friendly preparation workflows. The growing prevalence of genetic disorders, the rising adoption of companion diagnostics, and the expanding applications of genomics in drug discovery have collectively reinforced the significance of robust sample preparation solutions. Furthermore, the global shift toward personalized healthcare is encouraging researchers and clinical laboratories to invest heavily in technologies that minimize hands-on time, reduce errors, and improve reproducibility.
The acceleration in genomic research activities and the declining cost of sequencing have intensified the requirement for efficient, scalable, and high-yield sample preparation systems. Innovations in microfluidic technologies, the launch of integrated workstations, and the development of reagent kits tailored for specific applications are driving competitive differentiation in the market. For instance, library preparation and target enrichment workflows are increasingly being optimized for minimal sample input while maximizing sequencing accuracy and throughput. According to industry reports, the demand for NGS-based diagnostic testing is forecast to witness exponential growth, fueled by expanding cancer genomics programs, infectious disease surveillance, and pharmacogenomics research. However, the market continues to face challenges such as high instrument and reagent costs, complex regulatory requirements for clinical-grade sequencing, and the need for specialized technical expertise in workflow optimization.
Geographically, North America dominates the NGS Sample Preparation Market, underpinned by its robust healthcare infrastructure, significant investment in genomics research, and early adoption of precision medicine initiatives. The U.S., in particular, benefits from strong funding support from government bodies such as the NIH, fostering the rapid deployment of sequencing technologies in clinical and research settings. Europe holds a substantial share as well, driven by advancements in molecular diagnostics, collaborative genomic initiatives across EU member states, and an established base of biotechnology companies. Meanwhile, the Asia Pacific region is poised for the fastest growth during the forecast period, supported by large-scale genomic projects in China, India, and Japan, along with rising investments in biotechnology infrastructure. Countries in Latin America and the Middle East & Africa are gradually expanding their NGS capabilities, primarily through public-private partnerships and collaborations with global sequencing solution providers.
Major market player included in this report are:
• Illumina, Inc.
• Thermo Fisher Scientific Inc.
• Agilent Technologies, Inc.
• QIAGEN N.V.
• PerkinElmer, Inc.
• F. Hoffmann-La Roche Ltd.
• Bio-Rad Laboratories, Inc.
• Takara Bio Inc.
• Oxford Nanopore Technologies Ltd.
• BGI Genomics Co., Ltd.
• Pacific Biosciences of California, Inc.
• Beckman Coulter, Inc. (Danaher Corporation)
• New England Biolabs, Inc.
• Hamilton Company
• Zymo Research Corporation
Global NGS Sample Preparation Market Report Scope:
• Historical Data – 2023, 2024
• Base Year for Estimation – 2024
• Forecast period - 2025-2035
• Report Coverage - Revenue forecast, Company Ranking, Competitive Landscape, Growth factors, and Trends
• Regional Scope - North America; Europe; Asia Pacific; Latin America; Middle East & Africa
• Customization Scope - Free report customization (equivalent up to 8 analysts’ working hours) with purchase. Addition or alteration to country, regional & segment scope*
The objective of the study is to define market sizes of different segments & countries in recent years and to forecast the values for the coming years. The report is designed to incorporate both qualitative and quantitative aspects of the industry within the countries involved in the study. The report also provides detailed information about crucial aspects, such as driving factors and challenges, which will define the future growth of the market. Additionally, it incorporates potential opportunities in micro-markets for stakeholders to invest, along with a detailed analysis of the competitive landscape and product offerings of key players. The detailed segments and sub-segments of the market are explained below:
By Product:
• Reagents & Consumables
• Workstations
By Workflow:
• Library Prep
• Target Enrichment
By Sample Type:
• DNA
By Application:
• Diagnostics
• Drug Discovery
By Method:
• Microfluidic
• Automated
By End User:
• (End User segmentation details to be included if specified)
By Region:
North America
• U.S.
• Canada
Europe
• UK
• Germany
• France
• Spain
• Italy
• ROE
Asia Pacific
• China
• India
• Japan
• Australia
• South Korea
• RoAPAC
Latin America
• Brazil
• Mexico
Middle East & Africa
• UAE
• Saudi Arabia
• South Africa
• Rest of Middle East & Africa
Key Takeaways:
• Market Estimates & Forecast for 10 years from 2025 to 2035.
• Annualized revenues and regional level analysis for each market segment.
• Detailed analysis of geographical landscape with Country level analysis of major regions.
• Competitive landscape with information on major players in the market.
• Analysis of key business strategies and recommendations on future market approach.
• Analysis of competitive structure of the market.
• Demand side and supply side analysis of the market.

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Table of Contents

Table of Contents
Chapter 1. Global NGS Sample Preparation Market Report Scope & Methodology
1.1. Research Objective
1.2. Research Methodology
1.2.1. Forecast Model
1.2.2. Desk Research
1.2.3. Top Down and Bottom-Up Approach
1.3. Research Attributes
1.4. Scope of the Study
1.4.1. Market Definition
1.4.2. Market Segmentation
1.5. Research Assumption
1.5.1. Inclusion & Exclusion
1.5.2. Limitations
1.5.3. Years Considered for the Study

Chapter 2. Executive Summary
2.1. CEO/CXO Standpoint
2.2. Strategic Insights
2.3. ESG Analysis
2.4. Key Findings

Chapter 3. Global NGS Sample Preparation Market Forces Analysis
3.1. Market Forces Shaping The Global NGS Sample Preparation Market (2024–2035)
3.2. Drivers
3.2.1. Rising adoption of precision medicine and companion diagnostics
3.2.2. Expanding applications of genomics in diagnostics and drug discovery
3.2.3. Declining sequencing costs and advancements in high-throughput technologies
3.3. Restraints
3.3.1. High costs of instruments, reagents, and consumables
3.3.2. Complex regulatory requirements for clinical-grade sequencing
3.4. Opportunities
3.4.1. Emergence of automation-friendly and microfluidic-based sample preparation workflows
3.4.2. Expansion of genomic research programs in emerging economies

Chapter 4. Global NGS Sample Preparation Industry Analysis
4.1. Porter’s 5 Forces Model
4.1.1. Bargaining Power of Buyer
4.1.2. Bargaining Power of Supplier
4.1.3. Threat of New Entrants
4.1.4. Threat of Substitutes
4.1.5. Competitive Rivalry
4.2. Porter’s 5 Force Forecast Model (2024–2035)
4.3. PESTEL Analysis
4.3.1. Political
4.3.2. Economical
4.3.3. Social
4.3.4. Technological
4.3.5. Environmental
4.3.6. Legal
4.4. Top Investment Opportunities
4.5. Top Winning Strategies (2025)
4.6. Market Share Analysis (2024–2025)
4.7. Global Pricing Analysis And Trends 2025
4.8. Analyst Recommendation & Conclusion

Chapter 5. Global NGS Sample Preparation Market Size & Forecasts by Product 2025–2035
5.1. Market Overview
5.2. Global NGS Sample Preparation Market Performance – Potential Analysis (2025)
5.3. Reagents & Consumables
5.3.1. Top Countries Breakdown Estimates & Forecasts, 2024–2035
5.3.2. Market Size Analysis, by Region, 2025–2035
5.4. Workstations
5.4.1. Top Countries Breakdown Estimates & Forecasts, 2024–2035
5.4.2. Market Size Analysis, by Region, 2025–2035

Chapter 6. Global NGS Sample Preparation Market Size & Forecasts by Workflow 2025–2035
6.1. Market Overview
6.2. Global NGS Sample Preparation Market Performance – Potential Analysis (2025)
6.3. Library Preparation
6.3.1. Top Countries Breakdown Estimates & Forecasts, 2024–2035
6.3.2. Market Size Analysis, by Region, 2025–2035
6.4. Target Enrichment
6.4.1. Top Countries Breakdown Estimates & Forecasts, 2024–2035
6.4.2. Market Size Analysis, by Region, 2025–2035

Chapter 7. Global NGS Sample Preparation Market Size & Forecasts by Sample Type 2025–2035
7.1. Market Overview
7.2. Global NGS Sample Preparation Market Performance – Potential Analysis (2025)
7.3. DNA
7.3.1. Top Countries Breakdown Estimates & Forecasts, 2024–2035
7.3.2. Market Size Analysis, by Region, 2025–2035

Chapter 8. Global NGS Sample Preparation Market Size & Forecasts by Application 2025–2035
8.1. Market Overview
8.2. Global NGS Sample Preparation Market Performance – Potential Analysis (2025)
8.3. Diagnostics
8.3.1. Top Countries Breakdown Estimates & Forecasts, 2024–2035
8.3.2. Market Size Analysis, by Region, 2025–2035
8.4. Drug Discovery
8.4.1. Top Countries Breakdown Estimates & Forecasts, 2024–2035
8.4.2. Market Size Analysis, by Region, 2025–2035

Chapter 9. Global NGS Sample Preparation Market Size & Forecasts by Method 2025–2035
9.1. Market Overview
9.2. Global NGS Sample Preparation Market Performance – Potential Analysis (2025)
9.3. Microfluidic
9.3.1. Top Countries Breakdown Estimates & Forecasts, 2024–2035
9.3.2. Market Size Analysis, by Region, 2025–2035
9.4. Automated
9.4.1. Top Countries Breakdown Estimates & Forecasts, 2024–2035
9.4.2. Market Size Analysis, by Region, 2025–2035

Chapter 10. Global NGS Sample Preparation Market Size & Forecasts by Region 2025–2035
10.1. Global NGS Sample Preparation Market, Regional Market Snapshot
10.2. Top Leading & Emerging Countries
North America NGS Sample Preparation Market
10.3. U.S. NGS Sample Preparation Market
10.3.1. Product breakdown size & forecasts, 2025–2035
10.3.2. Workflow breakdown size & forecasts, 2025–2035
10.4. Canada NGS Sample Preparation Market
10.4.1. Product breakdown size & forecasts, 2025–2035
10.4.2. Workflow breakdown size & forecasts, 2025–2035
Europe NGS Sample Preparation Market
10.5. UK NGS Sample Preparation Market
10.5.1. Product breakdown size & forecasts, 2025–2035
10.5.2. Workflow breakdown size & forecasts, 2025–2035
10.6. Germany NGS Sample Preparation Market
10.6.1. Product breakdown size & forecasts, 2025–2035
10.6.2. Workflow breakdown size & forecasts, 2025–2035
10.7. France NGS Sample Preparation Market
10.7.1. Product breakdown size & forecasts, 2025–2035
10.7.2. Workflow breakdown size & forecasts, 2025–2035
10.8. Spain NGS Sample Preparation Market
10.8.1. Product breakdown size & forecasts, 2025–2035
10.8.2. Workflow breakdown size & forecasts, 2025–2035
10.9. Italy NGS Sample Preparation Market
10.9.1. Product breakdown size & forecasts, 2025–2035
10.9.2. Workflow breakdown size & forecasts, 2025–2035
10.10. Rest of Europe NGS Sample Preparation Market
10.10.1. Product breakdown size & forecasts, 2025–2035
10.10.2. Workflow breakdown size & forecasts, 2025–2035
Asia Pacific NGS Sample Preparation Market
10.11. China NGS Sample Preparation Market
10.11.1. Product breakdown size & forecasts, 2025–2035
10.11.2. Workflow breakdown size & forecasts, 2025–2035
10.12. India NGS Sample Preparation Market
10.12.1. Product breakdown size & forecasts, 2025–2035
10.12.2. Workflow breakdown size & forecasts, 2025–2035
10.13. Japan NGS Sample Preparation Market
10.13.1. Product breakdown size & forecasts, 2025–2035
10.13.2. Workflow breakdown size & forecasts, 2025–2035
10.14. Australia NGS Sample Preparation Market
10.14.1. Product breakdown size & forecasts, 2025–2035
10.14.2. Workflow breakdown size & forecasts, 2025–2035
10.15. South Korea NGS Sample Preparation Market
10.15.1. Product breakdown size & forecasts, 2025–2035
10.15.2. Workflow breakdown size & forecasts, 2025–2035
10.16. Rest of APAC NGS Sample Preparation Market
10.16.1. Product breakdown size & forecasts, 2025–2035
10.16.2. Workflow breakdown size & forecasts, 2025–2035
Latin America NGS Sample Preparation Market
10.17. Brazil NGS Sample Preparation Market
10.17.1. Product breakdown size & forecasts, 2025–2035
10.17.2. Workflow breakdown size & forecasts, 2025–2035
10.18. Mexico NGS Sample Preparation Market
10.18.1. Product breakdown size & forecasts, 2025–2035
10.18.2. Workflow breakdown size & forecasts, 2025–2035
Middle East & Africa NGS Sample Preparation Market
10.19. UAE NGS Sample Preparation Market
10.19.1. Product breakdown size & forecasts, 2025–2035
10.19.2. Workflow breakdown size & forecasts, 2025–2035
10.20. Saudi Arabia NGS Sample Preparation Market
10.20.1. Product breakdown size & forecasts, 2025–2035
10.20.2. Workflow breakdown size & forecasts, 2025–2035
10.21. South Africa NGS Sample Preparation Market
10.21.1. Product breakdown size & forecasts, 2025–2035
10.21.2. Workflow breakdown size & forecasts, 2025–2035
10.22. Rest of Middle East & Africa NGS Sample Preparation Market
10.22.1. Product breakdown size & forecasts, 2025–2035
10.22.2. Workflow breakdown size & forecasts, 2025–2035

Chapter 11. Competitive Intelligence
11.1. Top Market Strategies
11.2. Illumina, Inc.
11.2.1. Company Overview
11.2.2. Key Executives
11.2.3. Company Snapshot
11.2.4. Financial Performance (Subject to Data Availability)
11.2.5. Product/Services Port
11.2.6. Recent Development
11.2.7. Market Strategies
11.2.8. SWOT Analysis
11.3. Thermo Fisher Scientific Inc.
11.4. Agilent Technologies, Inc.
11.5. QIAGEN N.V.
11.6. PerkinElmer, Inc.
11.7. F. Hoffmann-La Roche Ltd.
11.8. Bio-Rad Laboratories, Inc.
11.9. Takara Bio Inc.
11.10. Oxford Nanopore Technologies Ltd.
11.11. BGI Genomics Co., Ltd.
11.12. Pacific Biosciences of California, Inc.
11.13. Beckman Coulter, Inc. (Danaher Corporation)
11.14. New England Biolabs, Inc.
11.15. Hamilton Company
11.16. Zymo Research Corporation