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世界のDNAシーケンシング:研究、用途および臨床市場

Global DNA Sequencing: Research, Applied and Clinical Markets

 

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BCC Research
BCCリサーチ
2019年5月US$5,500
シングルユーザライセンス
351

サマリー

この調査レポートは世界のDNAシーケンシング市場を分析・予測したBCC Researchの市場調査報告書です。

Overview

Report Scope:

The scope of the report includes sequencing technologies, applications, industries, initiatives, patents and companies. The markets for sequencing products and services are given for the years 2017, 2018, and 2023.

This report reviews the main sequencing technologies and explains why genetic variation is important in clinical testing. It then discusses some of the significant research initiatives that impact sequencing applications. Of particular interest is a discussion of population-scale sequencing projects throughout the world, and their likely impact on the sequencing industry. The main market driving forces for sequencing products and services are listed and discussed.

The report quantifies the sequencing markets by delivered format, including sequencing workflow products (sample preparation kits and reagents, sequencing instruments and consumables, and informatics) and sequencing services (clinical diagnostics and sequencing services to applied market customers).
The sample preparation kits and reagents market is quantified by type, that is, DNA isolation and extraction; target enrichment; and library preparation. The sequencing instruments and consumables market given by platform (Sanger, NGS and 3GS) and by product type (instruments, consumables).

The sequencing services market is analyzed by end user application (applied, clinical, research and development) and by genome type (human, non-human). Within sequencing services, the applied market is analyzed by end user application (agriculture, biopharma, consumer, microbiology, population-scale genomics, synthetic biology, and other).

Also within sequencing services, the clinical market is analyzed and quantified on a number of levels, including by disease category (cardiovascular, clinical microbiology and infectious diseases, Mendelian disorders, metabolic/immune disorders, neurology, oncology, reproductive health, and transplant medicine); by sequenced region (single gene, targeted region/multi-gene, exome, whole genome, and metagenome); by assay type (screening/early detection, diagnosis, therapy guidance, monitoring).

Within the diagnostics market, the oncology, reproductive health and transplant medicine market segments are analyzed as follows. The oncology market segment is analyzed by assay type; by sequenced region; and by indication (bladder, brain, breast, colorectal, cancer unknown primary, gastrointestinal stromal tumor, kidney, leukemia/lymphoma, lung, melanoma, pan-cancer, prostate, thyroid, and other cancer). The reproductive health market segment is analyzed by assay type; sequenced region; and application (carrier screening, in-vitro fertilization, newborn screening and non-invasive prenatal screening). The transplant market segment is analyzed by assay type; sequenced region; and organ type (lung, heart, liver, and kidney).

Specific geographic markets are discussed, including North America, Europe, Asia-Pacific, and the rest of the world.

Industry sectors analyzed include Sequencing instruments; long-read sequencing; target enrichment; gene editing; informatics; blockchain; liquid biopsy; reproductive health diagnostics; consumer genomics; agriculture; and DNA data storage.

More than 200 companies in the sequencing industry are profiled in this report.

BCC Research provides a summary of the more than 200 of the main industry acquisitions and strategic alliances from January 2017 through March 2019, including key alliance trends.

Report Includes:

- 27 data tables and 79 additional tables
- An overview of global market for DNA sequencing and discussion of applications in research, applied and clinical markets
- Analyses of global market trends, with data from 2017, 2018, and projections of compound annual growth rates (CAGRs) through 2023
- Description of sequencing markets by workflow, including sample preparation products; sequencing instruments and consumables; informatics; and sequencing services
- Coverage of Sanger and next-generation technologies in detail
- Detailed description of key sequencing research & development programs such as American Gut Consortium, BabySeq and Blood Profiling Atlas
- A look at the current trends and recent developments in the market
- Company profiles of the major players of the market, including 23Andme Inc., Mayo Medical Laboratories, Novogene Co. Ltd., Qiagen NV, Roche Holding AG, Thermo Fisher Scientific Inc. and Zhejiang Dian Diagnostics Co. Ltd.



目次

Table of Contents

Table of Contents
Chapter 1 Introduction
Study Goals and Objectives
Reasons for Doing This Study
Scope of Report
Information Sources
Methodology
Geographic Breakdown
Analyst's Credentials
BCC Custom Research
Related BCC Research Reports
Chapter 2 Summary and Highlights
Chapter 3 Overview
Introduction
Sequencing Markets
Sequencing Growth Driving Forces
Sequencing Applications
Sequencing Industry
Chapter 4 Technology Background
Importance of DNA
Genetic Variation and Analysis
History of Sequencing
Sequencing Technologies
Sanger Sequencing
Next Generation Sequencing
Informatics Technologies
Base Calling
Mapping to a Reference Sequence
Variant Analysis
Clinical Sequencing Adoption Challenges
Chapter 5 Sequencing Initiatives
Sequencing Initiatives
American Gut Consortium
BabySeq
Blood Profiling Atlas
Cancer-ID
Cancer Moon Shots Program
China Precision Medicine Initiative
ClinGen
Epifemcare
France Genomic Medicine Plan
Friends of Cancer Research Project
Human Cell Atlas Consortium
Immunomonitor Consortium
Integration of Imaging and Fluid-based Tumor Monitoring in Cancer Therapy Program
Liquid Biopsies and Imaging for Improved Cancer Care
Lung-Map
Matchmaker Exchange
Metagenomics and Metadesign of Subways and Urban Biomes (MetaSub)
Million Veteran Program
Mind
MedSeq
National Microbiome Initiative
Next Generation Single Cell Analysis Program
Precancer Atlas
Precision Medicine Initiative
Prompt
QuIP Project
TopMed
Population Sequencing Programs
Chapter 6 Research and Applied Applications
Introduction
Research and Development Applications
Applied Applications
Direct to Consumer
Biopharma
Agriculture
Forensics
Microbiome
Synthetic Biology
Chapter 7 Clinical Applications
Introduction
Cancer Applications
Mendelian Disorders Applications
Reproductive Health Applications
Microbiology and Infectious Disease Applications
Complex Disorders Applications
Transplant Diagnostics Applications
Chapter 8 Sequencing Industry
Introduction
Sequencing Instruments Industry
Long Read Sequencing Industry
Target Enrichment and Amplification Industry
Gene Editing Industry
Sequencing Informatics Industry
Sequencing Data-Based Blockchain Industry
Liquid Biopsy Assay Industry
Reproductive Health Diagnostics Industry
Non-invasive Prenatal Testing Industry
Fetal Cell NIPT Industry
Agriculture Industry
Consumer Genomics Industry
DNA Data Storage Industry
Chapter 9 Acquisitions and Strategic Alliances
Acquisitions
Strategic Alliances
Key Trends
2017 Alliances
2018 Alliances
2019 Alliances
Chapter 10 Sequencing Markets
Growth Driving Forces
Sequencing Market
Sequencing Instruments and Consumables Market
Sample Prep Kits and Reagents Market
Informatics Market
Sequencing Services Market
Agriculture Market
Biopharma Market
Consumer Genomics Market
Microbiology Market
Population Genomics Market
Synthetic Biology Market
Clinical Diagnostic Sequencing Market
Cardiology Market
Clinical Microbiology and Infectious Disease Market
Mendelian Disorders Market
Metabolic/Immune Disorders Market
Neurology Market
Oncology Market
Reproductive Health Market
Transplant Market
Single Gene Market
Multigene/Hotspot Market
Exome Sequencing Market
Whole Genome Sequencing Market
Screening/Early Detection Market
Diagnosis Market
Therapy Guidance Market
Monitoring Market
Cancer Clinical Diagnostics Sequencing Market
Lung Cancer Market
Breast Cancer Market
Colorectal Cancer Market
Pan-Cancer Market
Other Cancers
Oncology Screening/Early Detection Market
Oncology Diagnosis Market
Oncology Therapy Guidance Market
Oncology Monitoring Market
Role of Novel Biomarkers for Oncology Therapy Guidance and Monitoring
Reproductive Health Markets
IVF Market
Newborn Screening Market
Carrier Screening Market
NIPT Market
Transplant Market
Geographical Market
Chapter 11 Patent Review/ New Developments
Circulating Tumor Cell Patents
Exosome Patents
Cell-free DNA Patents
Sequencing-Related Patent Disputes
Chapter 12 Company Profiles
3BILLION INC.
10X GENOMICS, INC.
23ANDME INC.
ADAPTIVE BIOTECHNOLOGIES INC.
ADMERA HEALTH
AGILENT TECHNOLOGIES INC.
ALCEDIAG
ALMAC GROUP LTD.
AMARANTUS BIOSCIENCE HOLDINGS INC.
AMBRY GENETICS
APERIOMICS INC.
ARCHER DX
ARUP LABORATORIES
ASTRIDBIO TECHNOLOGIES KFT.
ASURAGEN INC.
ATHENA DIAGNOSTICS INC.
ATRECA INC.
BASE4 INNOVATION LTD.
BAYLOR GENETICS
BECTON, DICKINSON AND CO.
BELLWETHER BIO INC.
BERRY GENOMICS CO. LTD.
BGI SHENZHEN
BIOARRAY S.L.
BIOCEPT INC.
BIODESIX INC.
BIOMARX INC.
BIO-RAD LABORATORIES INC.
BIO-TECHNE LTD.
BLUEPRINT GENETICS
BLUESTAR GENOMICS INC.
BOREAL GENOMICS
CAMBRIDGE EPIGENETIX LTD.
CANCER GENETICS
CAREDX INC.
CARIS LIFE SCIENCES
CEGAT GMBH
CELLMAX LIFE
CELSEE DIAGNOSTICS
CENTOGENE AG
CERGENTIS BV
CHRONIX BIOMEDICAL
CIRCULOGENE THERANOSTICS
CIRCULOMICS INC.
COFACTOR GENOMICS INC.
COLOR GENOMICS
COOPER SURGICAL INC.
CORIELL LIFE SCIENCES INC.
COSMOSID
CS GENETICS LTD.
CYGNUS BIOSCIENCES CO. LTD.
CYNVENIO BIOSYSTEMS INC.
DANAHER CORP.
DATAR CANCER GENETICS LTD.
DARUI BIOTECHNOLOGY CO. LTD.
DEPIXUS
DEVYSER AB
DIACARTA INC.
DIAGNOMICS
DIPLOID
DIRECTED GENOMICS LLC
DIRECT GENOMICS CO. LTD.
DNA ELECTRONICS LTD.
DNANEXUS INC.
DOVETAIL GENOMICS LLC
ELECTRONIC BIOSCIENCES
ENVISION GENOMICS
EPIC SCIENCES INC.
ESPERITE NV
EUROFINS SCIENTIFIC
EXACT SCIENCES CORP.
EXPEDEON AG
EZLIFE BIO INC.
FABRIC GENOMICS
FLUXION BIOSCIENCES INC.
FREENOME INC.
FRY LABORATORIES LLC
FULL GENOMES CORPORATION
FUSION GENOMICS CORP.
GENAPSYS INC.
GENCOVE, INC.
GENDX BV
GENE BY GENE LTD.
GENEDX INC.
GENETICS RESEARCH LLC
GENOMATIX SOFTWARE GMBH
GENOME.ONE PTY LTD
GENOMIC EXPRESSION
GENOMIC HEALTH INC.
GENOME PROFILING LLC
GENOMNIA SRL
GENOMONCOLOGY
GENOSPACE
GENOOX
GENXOSOME TECHNOLOGIES INC.
GIGAGEN INC.
GOLDEN HELIX
GRAIL INC.
GRANDOMICS BIOSCIENCES CO. LTD.
GUARDANT HEALTH INC.
GUARDIOME
HELITEC
HELIX OPCO LLC
HISTOGENETICS LLC
HTG MOLECULAR DIAGNOSTICS INC.
HUMAN LONGEVITY INC.
ILLUMINA INC.
INEX INNOVATIONS EXCHANGE PTE. LTD.
INIVATA LTD.
INTERPACE DIAGNOSTICS LLC.
INVITAE
INVIVOSCRIBE INC.
IREPERTOIRE INC.
KAILOS GENETICS
KARIUS INC.
KELLBENX INC.
KEW INC.
KINGMED DIAGNOSTICS CENTER CO. LTD.
LABORATORY CORP. OF AMERICA INC.
LABORATORY FOR MOLECULAR MEDICINE
LEUCINE RICH BIO PVT. LTD.
LEXENT BIO INC.
LOOP GENOMICS
MACROGEN INC.
MAPMYGENOME
MAYO MEDICAL LABORATORIES
MDXHEALTH
MEDGENOME LABS PVT. LTD.
MENARINI SILICON BIOSYSTEMS SPA
MERCK KGAA
MOGENE LLC
MOLECULAR HEALTH GMBH
MOLECULARMD CORP.
MOLECULAR LOOP BIOSOLUTIONS LLC
MYRIAD GENETICS INC.
NANOSTRING TECHNOLOGIES INC.
NATERA INC.
NAVERIS INC.
NEOGENOMICS LABORATORIES
NEW ENGLAND BIOLABS
NEWGENE LTD.
NEW ONCOLOGY GMBH
NGENEBIO CO. LTD.
NIPD GENETICS
N-OF-ONE INC.
NOVOGENE CO. LTD.
NUGEN TECHNOLOGIES INC.
NUMEDII
NUPROBE INC.
NX PRENATAL INC.
OMNISEQ CORP.
ONCOCYTE CORP.
ONCODNA S.A.
ONEOME LLC
OTHRAM INC.
OXFORD NANOPORE TECHNOLOGIES LTD.
PACIFIC BIOSCIENCES OF CALIFORNIA INC.
PAIRNOMIX INC.
PANGAEA ONCOLOGY
PARADIGM DIAGNOSTICS INC.
PARSEQ LAB CO. LTD.
PATHWAY GENOMICS CORP.
PERKINELMER INC.
PERSONAL GENOME DIAGNOSTICS INC.
PERSONALIS INC.
PIERIANDX
POPULATION GENETICS TECHNOLOGIES LTD.
PORTABLE GENOMICS LLC
POSITIVE BIOSCIENCE
PRECIPIO INC.
PREDICINE INC.
PRENETICS
PREVENTIONGENETICS INC.
QIAGEN NV
QUANTAPORE INC.
QUANTUM BIOSYSTEMS INC.
QUANTUMDX
QUEST DIAGNOSTICS INC.
RARECYTE INC.
REAL TIME GENOMICS INC.
RESOLUTION BIOSCIENCE INC.
ROCHE HOLDING AG
SCREENCELL
SEEKIN
SEQUENCING.COM
SEVEN BRIDGES GENOMICS INC.
SINGLERA GENOMICS INC.
SISTEMAS GENOMICOS SL
SOFTGENETICS LLC
SOPHIA GENETICS
SPERA MEDICAL
STRAND LIFE SCIENCES PVT. LTD.
STRATOS GENOMICS INC.
SUPRATECH MICROPATH LABORATORY & RESEARCH INSTITUTE PVT. LTD.
SYAPSE
TAKARA BIO INC.
TEMPUS
THERMO FISHER SCIENTIFIC INC.
TRACE GENOMICS INC.
TROVAGENE INC.
TWINSTRAND BIOSCIENCES
TWO PORE GUYS INC.
UBIQUITY GENOMICS INC.
VELA DIAGNOSTICS
VERITAS GENETICS
VORTEX BIOSCIENCES
XING TECHNOLOGIES LLC
YIKON GENOMICS CO. LTD.
YOURGENE HEALTH PLC
ZHEJIANG DIAN DIAGNOSTICS CO. LTD.

List of Tables

List of Tables
Summary Table : Global Sequencing Market, by Delivered Format, Through 2023
Table 1 : Report Scope
Table 2 : Global Sequencing Market, by Product Type, Through 2023
Table 3 : Sequencing Market Growth Driving Forces
Table 4 : Sequencing End Users and Applications
Table 5 : Key Sequencing Industry Participants by Sector
Table 6 : DNA Chemical Building Blocks
Table 7 : DNA Translation and Transcription
Table 8 : Long-range DNA Structure
Table 9 : Genetic Variant Types
Table 10 : Molecular Diagnostic Technology Platforms
Table 11 : DNA Sequencing Historical Timeline
Table 12 : Sequencing Technology Development, 1990-2020
Table 13 : Cost to Sequence a Single Human Genome, 2001-2019
Table 14 : Sequencing Technology Summary
Table 15 : Sanger Sequencing Summary
Table 16 : Sanger Sequencing Improvements
Table 17 : Advanced Sequencing Technologies
Table 18 : Roche Next Generation Sequencing Workflow
Table 19 : Illumina Next Generation Sequencing Workflow
Table 20 : Thermo Fisher Next Generation Sequencing Workflow
Table 21 : Next Generation Sequencing Bioinformatics Workflow
Table 22 : Sequence Annotation Steps
Table 23 : Challenges for Implementing Clinical Next Generation Sequencing
Table 24 : Key Sequencing Research and Development Programs
Table 25 : Population Sequencing Projects, 2016-2019
Table 26 : Number of Sequencing Projects in GOLD Database, 2014-2018
Table 27 : Sequencing Projects in GOLD Database, by Sequencing Strategy, 2018
Table 28 : Main Sequencing Applications
Table 29 : Genetic Analysis Platform Comparison
Table 30 : Sequencing Impact on Agricultural Product Classes
Table 31 : Key Applications in Forensics/Human Identity Sequencing
Table 32 : Key Applications in Microbial Sequencing
Table 33 : Genetic Testing Scope
Table 34 : Key Applications for Sequencing-based Diagnostics
Table 35 : Cancer Applications
Table 36 : Mendelian Disorders Applications
Table 37 : Reproductive Health Screening Applications
Table 38 : Ethical Issues Associated with Prenatal and Newborn Screening
Table 39 : Microbiology and Infectious Disease Applications
Table 40 : Complex Disorder Applications
Table 41 : Transplant Diagnostics Applications
Table 42 : Subsectors within the Sequencing Industries
Table 43 : Advanced Sequencing Industry Company Positioning
Table 44 : End-to-End Sequencing Approaches
Table 45 : Long-Read Sequencing Industry
Table 46 : Target Enrichment Industry
Table 47 : Gene Editing Tools Industry
Table 48 : Agricultural Gene Editing Industry
Table 49 : Sequencing Informatics Industry
Table 50 : Sequencing Data-Based Blockchain Industry
Table 51 : Liquid Biopsy Assay Industry: Company Focus
Table 52 : Example of NGS-based Liquid Biopsy Market Differentiation
Table 53 : NIPT Industry
Table 54 : Estimated Number of NIPT Tests, by Company, 2018
Table 55 : Germany NGS-based Non-invasive Prenatal Diagnostic Companies, 2017
Table 56 : NIPT Test Licensing, by Country
Table 57 : Fetal Cell NIPT Industry
Table 58 : Key Players in Synthetic Biology Agriculture Industry
Table 59 : Key Players in Consumer Genomics Industry
Table 60 : DNA Data Storage Industry Key Participants
Table 61 : Sequencing Industry Acquisitions, January 2017-March 2019
Table 62 : Sequencing Industry Strategic Alliances, January 2017- March 2019
Table 63 : Sequencing Market Growth Driving Forces
Table 64 : Global Sequencing Market, by Format, Through 2023
Table 65 : Global Instruments and Consumables Market, by Product Type, Through 2023
Table 66 : Global Sequencing Instruments and Consumables Market, by Product Generation, Through 2023
Table 67 : Global Sample Preparation Market, by Product Type, Through 2023
Table 68 : Global Sequencing Services Market, by End User, Through 2023
Table 69 : Global Sequencing Services Market, by Genome Type, Through 2023
Table 70 : Global Applied Sequencing Services Market, by Application, Through 2023
Table 71 : Synthetic Biology Growth Driving Forces
Table 72 : Global Clinical Diagnostics Sequencing Market, by Disease Category, Through 2023
Table 73 : Examples of Dilated Cardiomyopathy Test Providers
Table 74 : Microbial Sequencing Landscape
Table 75 : Multiple Sclerosis Diagnostic Technologies
Table 76 : Global Clinical Diagnostics Sequencing Market, by Sequenced Region, Through 2023
Table 77 : Global Clinical Diagnostics Sequencing Market, by Test Purpose, Through 2023
Table 78 : NGS-based Preventive Genetic Screening Tests
Table 79 : Global Cancer Clinical Diagnostics Sequencing Market, by Indication, Through 2023
Table 80 : National Institute of Health Liquid Biopsy Early Detection Initative
Table 81 : Five-Year Survival Rate for Ovarian Cancer
Table 82 : Molecular Thyroid Nodule Classifier Test Company Positioning
Table 83 : Global Clinical Diagnostics Oncology Sequencing Market, by Test Purpose, Through 2023
Table 84 : MRI and Liquid Biopsy Methods
Table 85 : Early Detection Tissue of Origin Approaches
Table 86 : TMB Diagnostics Landscape
Table 87 : Global Clinical Diagnostics Sequencing Cancer Market, by Test Complexity, Through 2023
Table 88 : Global Clinical Reproductive Health Market, by Test Application, Through 2023
Table 89 : Global Sequencing-based NIPT Market, by Risk Type, Through 2023
Table 90 : Global Reproductive Health Clinical Sequencing Market, by Sequenced Region, Through 2023
Table 91 : Global Reproductive Health Clinical Sequencing Market, by Analysis Type, o
Table 92 : Global Transplant Clinical Sequencing Market, by Analysis Purpose, Through 2023
Table 93 : Global Transplant Clinical Sequencing Market, by Sequenced Region, Through 2023
Table 94 : Global Transplant Clinical Sequencing Market, by Organ Type, Through 2023
Table 95 : Transplant Procedures Performed in the United States, 2016-2018
Table 96 : Global Sequencing Market, by Region, Through 2023
Table 97 : Global Sequencing Workflow Products Market, by Region, Through 2023
Table 98 : Global Sequencing Services Market, by Region, Through 2023
Table 99 : Global Clinical Diagnostics Sequencing Market, by Region, Through 2023
Table 100 : CTC-related Patents, by Region, 2008-2018
Table 101 : Exosome-related Patents, by Region, 2008-2018
Table 102 : cfDNA-related Patents, by Region, 2008-2018
Table 103 : Status of Liquid Biopsy and Sequencing-related Patent Disputes
Table 104 : Data Generated by Platforms
Table 105 : Sensitivity to Detect Drug Resistant Mutations in Viruses

List of Figuresはメールでお送りいたします。データリソースまでお申し付けください。

 

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